子宫颈癌患者NSRH手术后性生活质量的研究  

Comparison of sexual life quality after nerve-sparing radical hysterectomy in patients with cervical cancer

作　　者：吴春华 霍智锋[1] 曾喆晟 吕照玲 郑莉[1] WU Chun-hua;HUO Zhi-feng;ZENG Zhe-sheng;LV Zhao-ling;ZHENG Li(Department of Obstetrics and Gynecology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;不详)

机构地区：[1]南方医科大学南方医院,广州510515

出　　处：《妇产与遗传（电子版）》2021年第4期39-43,共5页Obstetrics-Gynecology and Genetics (Electronic Edition)

基　　金：广东省卫生健康适宜技术推广项目(202006281522049338)。

摘　　要：目的比较中国早期子宫颈癌患者接受保留神经的广泛性全子宫切除术与广泛性全子宫切除术术后性生活质量情况。方法通过医院的病案管理系统查阅南方医科大学南方医院2015年至2017年所有宫颈癌住院病例,从976例接受了手术治疗的患者中筛选出符合条件的病例,采用子宫颈癌患者生活质量问卷调查表中关于评价性生活质量的项目,从症状(性焦虑、阴道功能)和功能(性活跃、性享受)两方面进行评估。结果根据入排标准共有79例患者入选,其中广泛性全子宫切除术组共54例;保留神经的广泛性全子宫切除术组共25例。(1)术后不同时间点两组间性焦虑、阴道功能、性活跃及性享受差异均无统计学意义。(2)动态对比术前及术后6个月、1年、2年性生活质量提示术后6个月时性焦虑达到高峰,后逐步缓解。(3)术后与术前各时间点阴道功能评分差异无统计学意义。(4)术后不同时间点性活跃与性享受与术前相比差异无统计学意义。结论对于早期子宫颈癌患者,保留神经的广泛性全子宫切除术与广泛性全子宫切除术均不能改善患者术后的性生活质量。Objective To compare the sexual life quality of Chinese patients with early cervicalcancer undergoing nerve-sparing radical hysterectomy(NSRH)and radical hysterectomy(RH).MethodsThis study screened eligible cases from 976 Chinese cervical cancer patients whounderwent surgical treatment in Nanfang Hospital,Southern Medical University from 2015 to 2017.The items selected from the European Tumors and Research Treatment Center for Cervical CancerPatients Quality of Life Questionaire(EORTC QLQ-CX 24)were used to evaluate the quality ofpostoperative sexual life in terms of symptoms(sexual anxiety,vaginal function)and function(sexualactivity,sexual enjoyment).ResultsAccording to the enrollment conditions,79 patients wereenrolled,including 54 patients in RH group and 25 patients in the NSRH group.(1)There was nostatistical difference in sexual anxiety,vaginal function,sexual activity and sexual enjoymentbetween the two groups at different time points after surgery.(2)Dynamic comparison of the sexual lifequality before and at 6 months,1 year,and 2 years after surgery showed that sexual anxiety reacheda peak at 6 months after surgery,and then gradually eased.(3)Vaginal function scores at all time points after surgery were all worse than those before surgery.(4)There was no statistical difference between sexual activity and sexual enjoyment at different time points after and before surgery.ConclusionsFor patients with early cervical cancer,the quality of sexual life was not improve after RH and NSRH.

关 键 词：子宫颈癌 性生活质量 性功能障碍 保留神经的广泛性子宫切除术 

分 类 号：R737.33[医药卫生—肿瘤]