胃肠炎伴良性婴幼儿惊厥发生的影响因素分析  

Influencing factors of gastroenteritis associated with benign infantile convulsion

作　　者：潘旭 田培超[1] PAN Xu;TIAN Pei-chao(Department of Pediatrics,The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;Department of Pediatrics,Nanyang Central Hospital,Nanyang,Henan 473000,China)

机构地区：[1]郑州大学第一附属医院儿科,郑州450052 [2]南阳市中心医院儿科,河南南阳473000

出　　处：《医药论坛杂志》2022年第5期57-60,共4页Journal of Medical Forum

摘　　要：目的研究胃肠炎伴良性婴幼儿惊厥(BICE)发生的影响因素。方法选取2018年9月—2020年9月郑州大学第一附属医院收治的86例BICE患儿为观察组,同期选取50例普通急性胃肠炎患儿为对照组,对入组者临床资料、辅助检查结果、症状体征等进行回顾性分析,对比两组患儿各项资料,并采用多因素Logistic回归分析影响因素。结果观察组所有患儿精神状态均正常,81例患儿体温正常(94.19%),80例患儿出现呕吐症状(93.02%),每日大便次数≤3次58例(67.44%),大便性状多为水样或蛋花汤样,未见明显脱水情况。惊厥发作时间为胃肠炎病毒感染后第1~3 d 66例(76.74%),发病季节集中于秋冬季节59例(68.60%),惊厥持续时间≤5 min 73例(84.88%),惊厥发作次数为1次~2次74例(86.05%),全身性发作62例(72.09%);与对照组比较,观察组轮状病毒感染、惊厥家族史占比分别为52.32%、10.46%,均增高,血清锌、铁水平分别为(49.17±6.16)μmol/L、(10.08±2.55)μmol/L,均较对照组低(P<0.05);经多因素Logistic回归分析,血清锌、铁水平,轮状病毒感染及惊厥家族史均是BICE发生的影响因素。结论血清锌、铁水平偏低,惊厥家族史及轮状病毒感染均是BICE发生的影响因素,临床需加强重视。Objective To study the influencing factors of benign infantile convulsion with gastroenteritis(BICE).Methods A total of 86 children with BICE from September 2018 to September 2020 were selected as the observation group,and 50 children with common acute gastroenteritis were selected as the control group during the same period.The clinical data,auxiliary examination results,symptoms and signs of the enrolled children were retrospectively analyzed,and the data of the two groups were compared.Multivariate Logistic regression was used to analyze the influencing factors.Results In the observation group,all the children had normal mental status,81 children had normal body temperature(94.19%),80 children had vomiting symptoms(93.02%),and 58 children(67.44%)had stool times≤3 times per day.Most of the stool characteristics were water or egg flower soup,and no obvious dehydration was observed.The duration of convulsion was less than 5 min in 73 cases(84.88%),and the frequency of convulsion was 1~2 in 74 cases(86.05%).62 cases(72.09%)had systemic attacks.Compared with the control group,the incidence of rotavirus infection and family history of convulsion in the observation group were 52.32%and 10.46%,respectively,and the serum zinc and iron levels were(49.17±6.16)μmol/L and(10.08±2.55)μmol/L,respectively,lower than those in the control group(P<0.05).Multivariate Logistic regression analysis showed that serum zinc and iron levels,rotavirus infection and family history of convulsion were the influential factors for the occurrence of BICE.Conclusion Low levels of serum zinc and iron,family history of convulsations and rotavirus infection are the influencing factors of BICE,which should be paid more attention to clinically.

关 键 词：胃肠炎 婴幼儿 惊厥 影响因素 轮状病毒感染 惊厥家族史 

分 类 号：R725.7[医药卫生—儿科]