难治性幽门螺杆菌感染的处理:共识和争议  

Management of Refractory Helicobacter pylori Infection:Consensus and Controversy

作　　者：刘文忠[1] LIU Wenzhong(Division of Gastroenterology and Hepatology,Renji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai Institute of Digestive Disease,Shanghai 200001)

机构地区：[1]上海交通大学医学院附属仁济医院消化内科,上海市消化疾病研究所,200001

出　　处：《胃肠病学》2021年第7期385-388,共4页Chinese Journal of Gastroenterology

摘　　要：幽门螺杆菌(Hp)感染的危害已得到充分认识,根除Hp预防和治疗Hp相关疾病具有很高的成本-效益优势。“治疗所有Hp阳性者,除非有抗衡因素”的观点已被普遍接受。然而,目前临床Hp根除率逐渐下降,影响了Hp感染的防控。目标虽已统一,但具体实施时遇到困难,使得“难治性Hp感染”的处理成为当前研究热点。本文就“难治性Hp感染”定义的争议、造成“难治性”的原因和相关对策进行详细阐述。The harm of Helicobacter pylori(Hp)infection has been fully recognized,and the eradication of Hp to prevent and treat Hp-associated diseases is highly cost-effective.Now,the statement“Hp infected individuals should be offered eradication therapy,unless there are competing considerations”has been widely accepted.However,the eradication rate of Hp in clinical practice is gradually decreasing,which affects negatively the prevention and control of Hp infection.The goals are unified,but difficulties are encountered in the implementation.Therefore,the treatment of“refractory Hp infection”has become a hot research spot today.In this paper,the controversy over the definition of“refractory Hp infection”,the causes for“refractory”infection and related countermeasures are described in detail.

关 键 词：幽门螺杆菌 根除 难治性 共识 

分 类 号：R73[医药卫生—肿瘤]