莳萝精油及提取物的化学成分和药理活性的研究进展  

Research progress on chemical composition and pharmacological activities of dill essential oil and its extract

作　　者：刘恬恬 周高 勾林晶 赵异 曾红 戴河双 蔡强 陈玉欣 LIU Tian-tian;ZHOU Gao;GOU Lin-jing;ZHAO Yi;ZENG Hong;DAI He-shuang;CAI Qiang;CHENYu-xin(Key Laboratory of Fermentation Engineering(Ministry of Education),Department of Pharmaceutical Engineering,School of Food and Biological Engineering,Hubei University of Technology,Wuhan 430068,China;National“111”Center for Cellular Regulation and Molecular Pharmaceutics,Hubei University of Technology,Wuhan 430068,China;Department of Plant Science,School of Life Sciences,Wuhan University,Wuhan 430072,China;Xinjiang Production&Construction Corps,Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin,College of Life Sciences,Tarim University,Alaer,843300,China)

机构地区：[1]湖北工业大学生物工程与食品学院制药工程系发酵工程教育部重点实验室,湖北武汉430068 [2]湖北工业大学国家外专局/教育部细胞调控与分子药物学科创新“111”引智基地,湖北武汉430068 [3]武汉大学生命科学学院植物科学系,湖北武汉430072 [4]塔里木大学生命科学学院新疆生产建设兵团塔里木盆地生物资源保护利用重点实验室,新疆阿拉尔843300

出　　处：《中草药》2022年第8期2582-2596,共15页Chinese Traditional and Herbal Drugs

基　　金：湖北省自然科学基金项目(2020CFB197);新疆生产建设兵团塔里木盆地生物资源保护利用重点实验室开放课题(BRZD2002);湖北工业大学细胞调控与分子药物“111”引智基地青年学者国际合作研究项目(XBTK-2020003)。

摘　　要：莳萝为伞形科植物莳萝Anethum graveolens的全草,是一种典型的维吾尔族药物,在我国各地均有栽培或野生资源。莳萝精油是从莳萝全草中提取的植物挥发油,文献报道莳萝精油的主要成分为α-水芹烯、柠檬烯和香芹酮,莳萝提取物的主要成分为酚类及黄酮类化合物,其药理活性主要包括镇痛、抗炎、抗菌、抗氧化、抗肿瘤、抗糖尿病、降胆固醇、杀虫和肝保护等。综述了莳萝精油及提取物的化学成分和药理活性的相关研究,以期为莳萝的深入研究与应用提供参考,推动民族医药产业的现代化进程。Dill is the whole herb of Anethum graveolens in the Umbelliferous family.It is a typical Uyghur medicine, which is cultivated or wild all over China.Dill essential oil is the essential oil extracted from the whole plant.According to literatures, the main ingredients of dill essential oil are α-phellandrene, limonene and carvone, and the main ingredients of various of dill extracts are phenols and flavonoids.Its pharmacological activities mainly include analgesia, anti-inflammation, anti-bacteria, anti-oxidation, anti-cancer, antidiabetic, cholesterol-reducing, insecticidal, liver protection and so on.In this paper, the ingredients and pharmacological activities of dill essential oil and extract were reviewed, in order to provide reference for the further research and application of dill and promote the modernization and long-term development of national medicine industry.

关 键 词：民族药 莳萝 精油 α-水芹烯 柠檬烯 香芹酮 镇痛 抗炎 抗菌 抗氧化 抗肿瘤 抗糖尿病 

分 类 号：R286[医药卫生—中药学]