Specialized endoplasmic reticulum-derived vesicles in plants:Functional diversity,evolution,and biotechnological exploitation  

作　　者：Xie Li Xifeng Li Baofang Fan Cheng Zhu Zhixiang Chen 

机构地区：[1]College of Life Science,Key Laboratory of Marine Food Quality and Hazard Controlling Technology of Zhejiang Province,China Jiliang University,Hangzhou 310018,China [2]Department of Botany and Plant Pathology,Center for Plant Biology,Purdue University,West Lafayette IN 47907-2054,USA

出　　处：《Journal of Integrative Plant Biology》2022年第4期821-835,共15页植物学报（英文版）

基　　金：supported by China National Major Research and Development Plan (Grant No. 0111900);National Natural Science Foundation of China (Grant No. 32000143);Zhejiang Provincial Natural Science Foundation of China (Grant No. LQ20C020002) at China Jiliang University;by U.S. National Science Foundation (Grant No. IOS1456300 and IOS1758767) at Purdue University.

摘　　要：A central role of the endoplasmic reticulum(ER)is the synthesis,folding and quality control of secretory proteins.Secretory proteins usually exit the ER to enter the Golgi apparatus in coat protein complex II(COPII)-coated vesicles before transport to different subcellular destinations.However,in plants there are specialized ER-derived vesicles(ERDVs)that carry specific proteins but,unlike COPII vesicles,can exist as independent organelles or travel to the vacuole in a Golgi-independent manner.These specialized ERDVs include protein bodies and precursor-accumulating vesicles that accumulate storage proteins in the endosperm during seed development.Specialized ERDVs also include precursor protease vesicles that accumulate amino acid sequence KDEL-tailed cysteine proteases and ER bodies in Brassicales plants that accumulate myrosinases that hydrolyzes glucosinolates.These functionally specialized ERDVs act not only as storage organelles but also as platforms for signal-triggered processing,activation and deployment of specific proteins with important roles in plant growth,development and adaptive responses.Some specialized ERDVs have also been exploited to increase production of recombinant proteins and metabolites.Here we discuss our current understanding of the functional diversity,evolutionary mechanisms and biotechnological application of specialized ERDVs,which are associated with some of the highly remarkable characteristics important to plants.

关 键 词：endoplasmic reticulum-derived vesicles ER body GLUCOSINOLATES myrosinases precursor accumulating vesicles precursor protease vesicles PROLAMINS protein body ricinosomes zeins 

分 类 号：Q945[生物学—植物学]