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作 者:王月琳 李大可[2] 王德文 WANG Yuelin;LI Dake;WANG Dewen(School of Basic Medicine,Shandong University of Traditional Chinese Medicine,Shandong Province,Ji’nan 250013,China;Department of Rheumatology,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Shandong Province,Ji’nan 250013,China;Department of Traditional Chinese Medicine,Shandong Wendeng Orthopaedic Hospital,Shandong Province,Weihai 264400,China)
机构地区:[1]山东中医药大学基础医学院,山东济南250013 [2]山东中医药大学附属医院风湿病科,山东济南250013 [3]山东省文登整骨医院中医科,山东威海264400
出 处:《中国中医药现代远程教育》2022年第10期130-131,共2页Chinese Medicine Modern Distance Education of China
摘 要:干燥综合征起病多隐匿,临床表现多种多样,病情轻重程度各异,主要侵犯外分泌腺体。文章报道1例干燥综合征合并肾小管酸中毒患者,该患者以四肢无力,翻身,坐起困难等低血钾症典型症状为首发表现,补充诊断为肾小管酸中毒,行免疫学相关检查,诊断为干燥综合征。经激素相关治疗后原发病得到控制,电解质紊乱明显改善。通过该例诊疗过程,远端肾小管酸中毒或反复低血钾性周期性麻痹应考虑是否有潜在的自身免疫性疾病的可能性。探讨该病的发病机制与治疗,针对原发病的治疗以改善病情。Sjogren’s syndrome is often insidious,the clinical manifestations are varied,the severity of the disease varies,it mainly involves exocrine glands.This paper reports one case of patients with Sjogren’s syndrome with renal tubular acidosis,which presented with limb weakness,turn over and sit up difficult.The supplementary diagnosis was renal tubular acidosis.After immunological examination,the patient was diagnosed with Sjogren’s syndrome.The primary disease was controlled after hormone-related treatment,and electrolyte disturbances were significantly improved.Through the diagnosis and treatment in this case,distal renal tubular acidosis or repeated hypokalemia periodic paralysis should consider whether there is the possibility of underlying autoimmune disease.The pathogenesis and treatment of the disease and improve the condition of the primary disease was discussed.
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