中国9省市综合性医院缺血性中风住院患者临床特征分析  

Clinical Characteristics of Inpatients with Ischemic Stroke in General Hospitals of Nine Provinces and Cities in China

作　　者：杨薇[1,2] 谢雁鸣[2] 赵维[3] 庄严[4] 张罡 黎明全 YANG Wei;XIE Yanming;ZHAO Wei;ZHUANG Yan;ZHANG Gang;LI Mingquan(Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China;Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;Renmin University of China,Beijing 100872,China;PLA Navy General Hospital,Beijing,100048,China;Beijing FlashEx Technology Co.,Ltd.,Beijing 100080,China;The Third Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China)

机构地区：[1]长春中医药大学附属医院,长春130021 [2]中国中医科学院中医临床基础医学研究所,北京100700 [3]中国人民大学,北京100872 [4]中国人民解放军海军总医院,北京100048 [5]北京闪送科技有限公司,北京100080 [6]长春中医药大学附属第三临床医院,长春130021

出　　处：《世界中医药》2022年第6期858-863,共6页World Chinese Medicine

基　　金：国家“重大新药创制”科技重大专项(2009ZX09502-030);吉林省中医药管理局吉林省中医药科技项目(2020071)。

摘　　要：目的:借助医疗大数据分析缺血性中风住院患者人口学分布、住院特点和合并疾病特征以及用药规律。方法:采集全国9省市三级甲等综合医院信息系统(HIS)中缺血性中风住院患者信息,采用频数统计及关联规则方法,分析患者人口学信息、出入院情况、合并疾病及用药信息。结果:39777例缺血性中风患者,年龄中位数为68岁,主要集中于60~74岁年龄段,共12420例(31.22%),男女比为1.78∶1;入院病情急危者6940例(18.58%),住院天数15~28 d的共14477例(36.40%),患者主要在夏至及寒露2个节气入院;主要因急性脑梗死住院的共31176例(78.38%),入院诊断中风痰阻络证701例(74.97%),气虚血瘀证101例(11.76%);合并疾病前3位分别为高血压21938例(55.15%),糖尿病8287例(20.83%),冠心病7921例(19.91%);西药使用排首位的为阿司匹林,共20924例(52.60%),中成药使用排首位的为疏血通注射液,共9015例(22.66%),54.63%的患者住院期间同时使用了活血化瘀类药物及抗血小板药物。结论:缺血性中风住院患者年龄主要为60~89岁,男性多于女性,发病入院与节气可能相关,合并疾病主要为高血压、糖尿病和冠心病,中西药物使用排首位的分别为阿司匹林和疏血通注射液,且活血化瘀类中成药与抗血小板药物常联合使用。Objective:To analyze the demographic distribution,hospitalization characteristics,combined diseases,and medication regularity of inpatients with ischemic stroke with medical big data.Methods:The information of inpatients with ischemic stroke in the Hospital Information System(HIS)of tertiary grade A general hospitals in nine provinces and cities of China was collected.The demographic information,admissions and discharges,combined diseases,and medication information of patients were analyzed by frequency statistics and association rule.Results:Among the 39777 patients with ischemic stroke,the median age was 68 years,and 12420 cases(40.31%)were aged 60-74 years.The male/female ratio was 1.78∶1.A total of 6940 cases(18.58%)were in critical conditions at admission.There were 14477 cases(36.40%)hospitalized for 15-28 days,and the patients were admitted mainly in Summer Solstice and Cold Dew.A total of 31176 cases(78.38%)were hospitalized mainly due to acute cerebral infarction,and 701 cases(74.97%)were diagnosed with stroke due to phlegm blocking collaterals,and 101 cases(11.76%)with stroke due to qi deficiency and blood stasis.The top 3 combined diseases were hypertension(n=21938,55.15%),diabetes(n=8287,20.83%),and coronary heart disease(n=7921,19.91%).Aspirin ranked first in the use of western medicine,with 20924 cases involved(52.60%),and Shuxuetong Injection ranked first in the use of Chinese patent medicine,with 9015 cases involved(22.66%).The blood-activating and stasis-resolving drugs and antiplatelet drugs were used in combination by 54.63%of patients.Conclusion:The inpatients with ischemic stroke were mainly aged 60-89 years and dominated by males.The onset of the disease may be related to solar terms.The main combined diseases were hypertension,diabetes,and coronary heart disease.Aspirin and Shuxuetong Injection were the most commonly used Chinese and western medicines,and Chinese patent medicines for promoting blood circulation and removing blood stasis were often used in combination with antiplatelet dru

关 键 词：缺血性中风 住院患者特征 合并疾病 用药规律 医疗大数据 真实世界 医院信息系统 关联规则 

分 类 号：R743.3[医药卫生—神经病学与精神病学]