纳米银粒子的生物制备,表征及抗菌性研究  

Biosynthesis,Characterization and Antibacterial Activity of Silver Nanoparticles

作　　者：郭文阳 张宗源 潘梦诗 周留柱 亓兰达 徐宏光 张英涛 GUO Wenyang;ZHANG Zongyuan;PAN Mengshi;ZHOU Liuzhu;QI Landa;XU Hongguang;ZHANG Yingtao(Institute of Biology Co.Ltd.,Henan Academy of Science,Zhengzhou 450008,China)

机构地区：[1]河南省科学院生物研究所有限责任公司,郑州450008

出　　处：《河南科学》2022年第4期517-523,共7页Henan Science

基　　金：河南省科学院基本科研业务费项目(200605087)。

摘　　要：纳米银材料具有独特的理化性质,在医药、电子、家具材料等领域有广泛应用.利用黑曲霉HQ-1胞外生物合成纳米银,经过紫外可见分光光度计、透射电子显微镜、马尔文粒径分析仪等方式对合成的纳米银进行表征,并分析其抗菌性.结果发现,光照条件下,黑曲霉发酵滤液能与AgNO_(3)迅速反应生成纳米银,并且93.4%的粒径集中在10.0 nm以下;制备的纳米银稳定性强,对大肠杆菌和金黄色葡萄球菌均有良好的抑菌性.Nano-silver materials have unique physical and chemical properties and are widely used in medicine,electronics and furniture materials.In this paper,silver nanoparticles were synthesized extracellularly from Aspergillus niger HQ-1.Using UV-vis,TEM,Malvern particle size analyzer and other methods,we characterize the nano-silver,and analyze its antibacterial activity.The results showed that the filtrate of A.niger fermentation could react with AgNO_(3)rapidly to produce silver nanoparticles under light conditions,and the sizes of 93.4%particles are less than 10.0 nm.The prepared nano-silver has good stability and antibacterial activity against Escherichia coli and Staphylococcus aureus.

关 键 词：纳米银 黑曲霉HQ-1 抑菌性 AgNO_(3) 

分 类 号：O614.122[理学—无机化学]