Retina cell atlases of multiple species and an online platform for retina cell-type markers  

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作  者:Zaoxu Xu Changzheng Wang Min Chen Yuting Yuan Linzhou Li Zhen Huang Yue Yuan Huanming Yang Qi Wang Xingliang Zhang 

机构地区:[1]College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China [2]BGI-Shenzhen,Shenzhen,Guangdong 518083,China [3]Department of Computer Science,City University of Hong Kong,Hong Kong 999077,China [4]Tsinghua-Berkeley Shenzhen Institute(TBSI),Tsinghua University,Shenzhen,Guangdong 518055,China [5]Department of Physiology,School of Basic Medical Sciences,Binzhou Medical University,Yantai,Shandong 264003,China [6]Fujian Key Laboratory of Developmental and Neural Biology,College of Life Sciences,Fujian Normal University,Fuzhou,Fujian 350117,China [7]Cuiying Biomedical Research Center,Lanzhou University Second Hospital,Lanzhou,Gansu 730010,China [8]Institute of Pediatrics,Department of Pediatric Surgery,Shenzhen Children's Hospital,Shenzhen,Guangdong 51803&China [9]Department of Pediatrics,The Affiliated Hospital of Guangdong Medical University,Zhanjiang,Guangdong 524001,China

出  处:《Journal of Genetics and Genomics》2022年第3期262-265,共4页遗传学报(英文版)

基  金:supported by China National Gene Bank (CNGB);financially supported by funding from the National Natural Science Foundation of China (31670742);the Guangdong Natural Science Foundation (2021A1515011109)。

摘  要:The retina is a complex visual tissue that perceives light signals because of an exquisite orchestration of high cellular complexity(Fig. 1A). It is of great significance to explore the transcriptome diversity of each cell type for comprehensive understanding(Voigt et al.,2020b). Unlike conventional sequencing methods, single-cell RNAsequencing(scRNA-seq) and single-nucleus RNA-sequencing(snRNA-seq) accurately profile transcriptomic characterization of individual whole cells and nuclei, respectively.

关 键 词:CELL RETINA 

分 类 号:Q343[生物学—遗传学]

 

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