非酒精性脂肪性肝病与胰岛素抵抗的研究进展  

Research Progress on Non-alcoholic Fatty Liver Disease and Insulin Resistance

作　　者：崔姗姗[1] 刘英[1] 江霞[1] CUI Shan-shan;LIU Ying;JIANG Xia(Department of Endocrinology and Metabolism,Tianjin First Central Hospital,Tianjin 300010,China)

机构地区：[1]天津市第一中心医院内分泌与代谢科,天津300010

出　　处：《医学信息》2022年第10期66-69,共4页Journal of Medical Information

摘　　要：非酒精性脂肪性肝病是临床常见的肝病之一,尤其是随着饮食结构和生活方式的改变,其发生率不断上升。非酒精性脂肪性肝病发病机制较为复杂,具体机制尚未完全明确,目前普遍认为与遗传、环境、代谢密切相关。研究显示,胰岛素抵抗与非酒精性脂肪性肝病的发生、发展密切相关。本文主要综述胰岛素抵抗与非酒精性脂肪性肝病相关的脂肪因子以及两病的治疗方法,以期为非酒精性脂肪性肝病的预防及治疗提供参考。Nonalcoholic fatty liver disease(NAFLD)is one of the most common liver diseases in clinic.The incidence of NAFLD is increasing with the change of diet and lifestyle.The pathogenesis of non-alcoholic fatty liver disease is complex,and the specific mechanism has not been fully clarified.At present,it is generally believed that it is closely related to heredity,environment and metabolism.Studies have shown that insulin resistance is closely related to the occurrence and development of non-alcoholic fatty liver disease.This paper mainly reviews the fat factors related to insulin resistance and non-alcoholic fatty liver disease and the treatment methods of the two diseases,providing reference for the prevention and treatment of non-alcoholic fatty liver disease.

关 键 词：非酒精性脂肪性肝病 胰岛素抵抗 肥胖 

分 类 号：R575.5[医药卫生—消化系统]