多发脑胶质瘤白质受累部位特征的MRI表现  

Characteristics of the white matter involvement sites on MRI in patients with multiple gliomas

作　　者：李建瑞 许强 刘高平 周娴 骆仲强 潘灏 吴楠 卢光明 张志强 Li Jianrui;Xu Qiang;Liu Gaoping;Zhou Xian;Luo Zhongqiang;Pan Hao;Wu Nan;Lu Guangming;Zhang Zhiqiang(Department of Diagnostic Radiology,Nanjing 210002,China;Department of Neurological Surgery,Nanjing 210002,China;Department of Pathology,Nanjing 210002,China)

机构地区：[1]东部战区总医院放射诊断科,南京210002 [2]东部战区总医院神经外科,南京210002 [3]东部战区总医院病理科,南京210002

出　　处：《中华医学杂志》2022年第17期1311-1314,共4页National Medical Journal of China

基　　金：国家重点研发计划(2018YFA0701703);国家自然科学基金(81530054)。

摘　　要：本研究回顾性分析了多发脑胶质瘤122例及单发脑胶质瘤183例。多发脑胶质瘤中男74例,女48例,年龄18~83(53±13)岁;单发脑胶质瘤中男104例,女79例,年龄10~84(51±14)岁。采用基于标准空间的病灶分析方法构建多发脑胶质瘤空间分布频次热图,观察其白质受侵犯的部位特征。与单发脑胶质瘤组相比,多发脑胶质瘤组空间分布更多出现在室管膜下区、胼胝体区及扣带回(P<0.001),多发胶质瘤白质受累区更为广泛,以连合纤维(胼胝体体部,P<0.05)和联络纤维(扣带、穹隆,0.05<P<0.10)区受累频次更多。多发脑胶质瘤的大脑空间分布及白质受侵具有一定的部位特征性。The retrospective study included 122 cases of multiple glioma and 183 cases of single glioma.Of these,there were 74 males and 48 female with multiple gliomas,aged 18 to 83(53±13)years,and 104 males and 79 females with single gliomas,aged 10 to 84(51±14)years.A standard spatial-based lesion analysis method was used for constructing a spatially distributed frequency heatmap of multiple gliomas,to observe the characteristics of their white matter invasion sites.The spatial distribution was more frequent in the subventricular zone,corpus callosum and cingulate gyrus in the multiple glioma group compared to the single glioma group(P<0.001).The white matter areas of multiple gliomas were more extensively involved,with more frequent involvement of the conjoined fibers(corpus callosum,P<0.05)and contact fibers(cingulate,dome,0.05<P<0.10)areas.The spatial distribution of the brain and the white matter invasion of multiple gliomas have certain site specificity.

关 键 词：神经胶质瘤 多发 空间分布 白质 脑图谱 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学]