宫颈电环切术治疗宫颈上皮内瘤样病变效果及与术后妊娠结局、分娩方式关系  

Clinical effect of loop electrosurgical excision procedure for treating patients with cervical intraepithelial neoplasia and its correlation with their pregnancy outcomes and delivery mode

作　　者：许丽丽 周后晟 周颜 刘春华 柒铭铭 XU Lili;ZHOU Housheng;ZHOU Yan;LIU Chunhua;QI Mingming(Zhuzhou Central Hospital,Zhuzhou,Hunan Province,412000)

机构地区：[1]湖南省株洲市中心医院,412000

出　　处：《中国计划生育学杂志》2022年第4期869-873,共5页Chinese Journal of Family Planning

摘　　要：目的:分析宫颈上皮内瘤样病变(CIN)应用宫颈电环切术(LEEP)临床效果及与妊娠结局、分娩方式的相关性。方法:回顾性选取2018年1月-2019年10月本院诊治的CIN患者60例,根据手术的不同分为LEEP组和宫颈冷刀切术(CKC)组,分析比较两组手术时间、术中出血量、住院时间、愈合时间、妊娠结局、分娩方式等,分析各指标间相关性。结果:LEEP组手术时间(7.8±2.2min)、术中出血量(10.4±1.7ml)、住院时间(5.3±2.5d)、愈合时间(28.6±4.3d)均低于CKC组(P<0.05)。LEEP组妊娠结局与手术方式(0.551)、手术时间(0.538)呈中度正相关性,与术中出血量(0.445)呈低度正相关;分娩方式与手术时间(0.557)、术中出血量(0.682)、手术方式(0.556)呈中度正相关性(均P<0.05)。造成不良妊娠结局的独立危险因素有手术时间、吸烟史、流产史、胎次等。LEEP组并发症发生率(13.3%)小于CKC组(46.7%)(P<0.05)。结论:CIN患者应用LEEP可缩短手术时间、减少出血量,加快患者康复,减少不良妊娠结局,改善分娩方式。Objective:To analyze the clinical effect of loop electrosurgical excision procedure(LEEP)for treating patients with cervical intraepithelial neoplasia(CIN),and to study its correlation with the pregnancy outcomes and delivery mode of the patients.Methods:60patients with CIN from October 2019to January 2018were selected retrospectively,and these patients were divided into two groups according to the different cervical operative method.The patients in the experimental group were given LEEP,and the patients in the control group were given cold knife conization(CKC).The operation time,the intraoperative blood loss,the time of hospital stay,the healing time,the pregnancy outcomes,and the delivery mode of the patients were analyzed and were compared between the two groups.The relationships among the operation time,the intraoperative blood loss,the time of hospital stay,the healing time,the pregnancy outcomes,and the delivery mode of the patients were also analyzed.Results:The operative time(7.8±2.2 min),the intraoperative blood loss(10.4±1.7ml),the time of hospital stay(5.3±2.5d),and the healing time(28.6±4.3d)of the patients in the experimental group were significantly lower than those of the patients in the control group(P<0.05).In the experimental group,the pregnancy outcomes of the patients was moderately positively correlated with their operative method(0.551)and their operative time(0.538),and was negatively correlated with their intraoperative blood loss(0.445).In the experimental group,the delivery mode of the patients was moderately positively correlated with their operation time(0.557),their intraoperative blood loss(0.682),and their operative mode(0.556)(all P<0.05).The independent risk factors of the adverse pregnancy outcomes were operative time,smoking history,abortion history,and number of pregnancy,etc.The incidence of complications(13.3%)of the patients in the experimental group was significantly lower than that(46.7%)of the patients in the control group(P<0.05).Conclusion:LEEP for treating the pat

关 键 词：宫颈上皮内瘤样病变 宫颈电环切术 临床效果 妊娠结局 分娩方式 相关性 

分 类 号：R737.33[医药卫生—肿瘤]