再普乐治疗老年性精神病性障碍80例疗效分析  

Efficacy Analysis of Zyprexa in 80 Cases of Senile Psychotic Disorder

作　　者：唐松林[1] Tang Song-lin(The First People's Hospital of Shaoyang City,Shaoyang 422039,Hunan Province,China)

机构地区：[1]湖南省邵阳市第一人民医院,湖南邵阳422039

出　　处：《中国社区医师》2022年第13期60-62,共3页Chinese Community Doctors

基　　金：邵阳地区老年性精神疾病防治知识科普活动效果观察(编号:S2021ZCKPZT0204)。

摘　　要：目的:分析对老年性精神性障碍患者应用再普乐(奥氮平片)治疗的临床疗效。方法:选取2021年2月-2022年2月湖南省邵阳市第一人民医院收治的老年性精神病性障碍患者80例为研究对象,依照随机数字表法对其进行分组,接受常规治疗的40例患者为对照组,在常规治疗基础上增加服用再普乐的40例患者为研究组,均治疗8周,比较两组患者治疗效果、精神障碍相关指标及日常生活能力评分。结果:研究组增加服用再普乐后治疗有效率明显高于对照组,差异有统计学意义(P<0.05)。治疗前两组患者的阳性、阴性症状量表(PANSS)评分、简明精神病量表(BPRS)评分、总体印象量表(CGI-SI)评分、日常生活能力(ADL)评分比较,差异无统计学意义(P>0.05);研究组增加服用再普乐治疗后PANSS评分、BPRS评分、CGI-SI评分均明显低于对照组,ADL评分明显高于对照组,差异有统计学意义(P<0.05)。结论:对老年性精神障碍患者使用再普乐治疗临床疗效显著。Objective:To analyze the clinical efficacy of Zyprexa(olanzapine)in the treatment of senile psychotic disorder.Methods:Eighty patients with senile psychotic disorder treated in the First People's Hospital of Shaoyang City from February 20219 to February 2022 were selected as the study subjects,they were divided into groups according to random number table method.The 40 patients receiving conventional treatment were taken as control group and 40 patients receiving Zyprexa on the basis of conventional treatment were taken as study group.All patients were treated for 8 weeks.The treatment effects,mental disorder related indicators and activity of daily living score of patients in the two groups were compared.Results:The effective rate of treatment in the study group after Zyprexa was added was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the scores of positive and negative syndrome scale(PANSS),brief psychiatric rating scale(BPRS),clinical global impression scale(CGI-SI)and activities of daily living(ADL)between the two groups before treatment(P>0.05).After Zyprexa was added,the scores of PANSS,BPRS and CGISI of the study group were significantly lower than those of the control group,while the ADL score of the study group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:Zyprexa has a significant clinical efficacy in the treatment of senile mental disorder.

关 键 词：再普乐 老年性 精神障碍 

分 类 号：R749[医药卫生—神经病学与精神病学]