黄斑中心凹旁渗出性血管异常复合体研究进展  

Advances in the study of perifoveal exudative vascular anomalous complex

作　　者：梁雨辰 段佳良[1] 尚庆丽[1] Liang Yuchen;Duan Jialiang;Shang Qingli(Department of Ophthalmology,Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院眼科,石家庄050000

出　　处：《中华眼底病杂志》2022年第5期415-419,共5页Chinese Journal of Ocular Fundus Diseases

基　　金：河北省医学适用技术跟踪项目(GZ2021039)。

摘　　要：黄斑中心凹旁渗出性血管异常复合体(PEVAC)是近年来发现的以黄斑中心凹旁孤立动脉瘤病变伴有出血与硬性渗出为特征的一类疾病。其发病机制和病理进程现阶段尚未完全阐明。目前通过多模式影像学研究普遍认为PEVAC是特发性黄斑中心凹旁视网膜血管异常,并伴有黄斑囊样水肿(CME)及硬性渗出。临床易将其与糖尿病视网膜病变或视网膜静脉阻塞所致的视网膜微动脉瘤、动脉瘤型毛细血管扩张症、3型黄斑新生血管(Ⅰ期)混淆。PEVAC有一定的自愈性,部分动脉瘤及CME可在随访中自行消退。激光光凝是治疗PEVAC的有效措施。未来随着影像学技术的快速发展,对发病机制与诊疗策略研究的进展和理论的更新有望为PEVAC提供更有效的治疗手段。Perifoveal exudative vascular anomalous complex(PEVAC)are class of diseases characterized by isolated aneurysmal lesions of the perifovea with hemorrhage and hard exudates,which are found in recent years.Its pathogenesis and pathological process are not yet fully elucidated.The current consensus through multimodal imaging studies is that PEVAC is an idiopathic perifoveal retinal vascular abnormality with cystoid macular edema(CME)and hard exudate.It is not easily distinguished clinically from retinal microaneurysm due to diabetic retinopathy or retinal vein occlusion,aneurysmal telangiectasia,and type 3 macular neovascularization(stageⅠ).PEVAC is a partially self-healing property,and some aneurysms and CME may resolve on their own during follow-up period.Laser photocoagulation is an effective measure for the treatment of PEVAC.In the future,with the rapid development of imaging technology,the progress of research on pathogenesis and treatment strategies and the updating of theories are expected to provide more effective treatments for PEVAC.

关 键 词：综述 黄斑水肿 激光凝固术 黄斑中心凹旁渗出性血管异常复合体 

分 类 号：R774.5[医药卫生—眼科]