子宫颈癌前哨淋巴结活检技术的研究进展  

Research progress of sentinel lymph node biopsy technique in cervical cancer

作　　者：王亚婷 李斌 Wang Yating;Li Bin(Department of Gynecology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]国家癌症中心,国家肿瘤临床医学研究中心,中国医学科学院北京协和医学院肿瘤医院妇科,北京100021

出　　处：《中华肿瘤杂志》2022年第5期377-381,共5页Chinese Journal of Oncology

基　　金：首都卫生发展科研专项(首发2020-2-4024)。

摘　　要：子宫颈癌是中国女性最常见的妇科恶性肿瘤,严重危害女性健康。淋巴结转移是影响早期子宫颈癌预后和辅助治疗的最主要因素。传统的盆腔淋巴结清扫术一直是确定淋巴结转移情况的可靠手段,但其并发症发生率高,严重影响患者的生活质量。前哨淋巴结活检术(SLNB)的应用旨在高效、准确评估盆腔淋巴结转移状态,以避免不必要的淋巴结清扫术,达到个体化诊疗目的。探索高效的前哨淋巴结示踪方法和病理学检测方法是子宫颈癌SLNB临床应用的关键,了解最新相关临床研究进展,有助于SLNB早日应用于临床,使子宫颈癌患者受益。Cervical cancer is the most common gynecological malignant carcinoma in Chinese women,which seriously threatens women′s health.Lymph node metastasis is the most important factor affecting the prognosis and adjuvant treatment of patients with early cervical cancer.Conventional systematic lymphadenectomy has always been a reliable method to detect lymph node metastasis.However,this procedure may affect the quality of life of patients because of high risks of complications.Recently,sentinel lymph node biopsy(SLNB)has been researched aiming to assess the status of pelvic lymph node metastasis intraoperatively,avoid unnecessary lymphadenectomy and achieve the goal of individualized diagnosis and treatment.Exploring efficient tracing methods and pathological ultra-staging is the key to the clinical application of SLNB for cervical cancer,and understanding the latest relevant clinical research progress will help SLNB to be applied in the clinic as soon as possible to benefit patients with cervical cancer.

关 键 词：子宫颈肿瘤 前哨淋巴结活检术 病理超分期 研究进展 

分 类 号：R737.33[医药卫生—肿瘤]