非酒精性脂肪性肝病合并代谢综合征患者理化指标及舌象特征研究  

Study on physicochemical indexes and tongue features of patients with NAFLD complicated with metabolic syndrome

作　　者：段绍杰 刘尊敬[2] 陈佳良 姚树坤[3] DUAN Shao-jie;LIU Zun-jing;CHEN Jia-liang;YAO Shu-kun(Beijing University of Chinese Medicine(Beijing,100029),China;Department of Neurology,China-Japan Friendship Hospital(Beijing,100029),China;Department of Gastroenterology,China-Japan Friendship Hospital(Beijing,100029),China)

机构地区：[1]北京中医药大学研究生院,北京100029 [2]中日友好医院神经内科 [3]中日友好医院消化内科

出　　处：《中西医结合肝病杂志》2022年第5期403-405,409,共4页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

基　　金：国家科技支撑计划课题(No.2014BAI08B02);北京市科委G20工程创新研究十病十药研发项目(No.Z171100001717008);中央高校基本科研业务费专项资金;中日友好医院生物医学转化工程系列研究项目(No.PYBZ1815)。

摘　　要：目的:探讨非酒精性脂肪性肝病(NAFLD)合并代谢综合征(MS)患者的理化指标及舌象特征,为临床诊断和防治该病提供证据支持。方法:于北京某三甲医院连续性纳入确诊为NAFLD患者201例,于治疗前标准化采集相关临床资料及舌象照片,并经智能化颜色校正后导入舌象标注平台进行舌象特征提取,根据是否合并MS,分为合并MS组(101例)和非MS组(100例),比较两组患者的相关理化指标及舌象特征差异。结果:MS组患者暗红舌、深黄苔、较厚苔的发生率以及腹围、体重指数(BMI)、血压(SBP、DBP)、空腹血糖(GLU)、甘油三酯(TG)、同型半胱氨酸(HCY)、白细胞(WBC)、中性粒细胞(NEUT)水平显著高于非MS组,而HDL-C水平显著低于非MS组(P<0.05)。结论:NAFLD患者合并MS与暗红舌、深黄苔、较厚苔以及腹围、BMI、SBP、DBP、GLU、TG、HCY、WBC、NEUT水平密切相关,通过观察舌象特征及监测相关理化指标,对NAFLD合并MS的诊断和中西医结合防治具有重要临床意义。Objective:To explore the physicochemical indexes and tongue features of patients with nonalcoholic fatty liver disease(nonalcoholic fatty liver disease,NAFLD)complicated with metabolic syndrome(metabolic syndrome,MS).Methods:A total of 201 subjects diagnosed with NAFLD was continuously enrolled in a third-class hospital in Beijing.The relevant clinical data and tongue photos were collected standardized,and after intelligent color correction,the tongue image was imported into the tongue image labeling platform for tongue image feature extraction.According to the combination of MS,the patients were divided into the MS group(101cases)and non-MS group(100 cases).The differences in relevant physicochemical indexes and tongue features between the two groups were compared.Results:The incidence of the dark red tongue,deep yellow coating,and thicker coating and the levels of abdominal circumference,BMI,SBP,DBP,GLU,TG,HCY,WBC,and NEUT in the MS group were significantly higher than those in non-MS group,while the level of HDL-C in MS group was significantly lower than that in non-MS group(P<0.05).Conclusion:NAFLD patients complicated with MS is closely related to dark red tongue,deep yellow coating,thicker coating,abdominal circumference,BMI,SBP,DBP,GLU,TG,HCY,WBC,NEUT and so on.The observation of tongue features and the monitoring of related physicochemical indexes,it has important clinical significance for the prevention and treatment of NAFLD and MS by integrated traditional Chinese and western medicine.

关 键 词：非酒精性脂肪性肝病 代谢综合征 舌象特征 理化指标 

分 类 号：R575.5[医药卫生—消化系统]