影像学无创评估肝纤维化研究进展  

Advancements of imaging noninvasive evaluation on liver fibrosis

作　　者：刘兴利 芮茂萍[3] 周尚彪 吕梁[1,2] LIU Xingli;RUI Maoping;ZHOU Shangbiao;LYU Liang(Department of Radiology,the First People's Hospital of Yunnan Province,Kunming 650032,China;Department of Radiology,the Affiliated Hospital of Kunming University of Science and Technology,Kunming 650032,China;Department of Magnetic Resonance,the First People's Hospital of Yunnan Province,Kunming 650032,China;Department of Radiology,the First People's Hospital of Yunnan Province,New Kunhua Hospital,Anning 650301,China)

机构地区：[1]云南省第一人民医院放射科,云南昆明650032 [2]昆明理工大学附属医院放射科,云南昆明650032 [3]云南省第一人民医院磁共振科,云南昆明650032 [4]云南省第一人民医院新昆华医院放射科,云南安宁650301

出　　处：《中国介入影像与治疗学》2022年第5期310-313,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：2019 SKY影像科研基金(Z-2014-07-1912-17);云南省“万人计划”名医人才专项(YNWR-MY-2019-011)。

摘　　要：肝纤维化是慢性肝病进展后病理改变,为肝硬化及肝细胞癌发展的重要环节。早期诊断肝纤维化和准确分期对尽早干预意义重大。肝穿刺活检是临床诊断肝纤维化的金标准,但患者接受度差,且无法评估肝脏整体。近年来,影像学技术如超声弹性成像、MRI、CT、PET/CT及人工智能逐渐用于评估肝纤维化。本文就影像学无创评估肝纤维化研究进展进行综述。Liver fibrosis is the pathological change in progression of chronic liver disease,which is an important link in the development of liver cirrhosis and hepatocellular carcinoma(HCC).Early diagnosis and staging of liver fibrosis are of great significance.Liver biopsy is the golden standard for clinical diagnosis of liver fibrosis,but being poorly accepted by patients and can not be used to evaluate the whole liver.Recent years,imaging technologies,including ultrasound elastography,MRI,CT and PET/CT,as well as artificial intelligence(AI)had gradually been used to evaluate liver fibrosis.The advancements of imaging noninvasive evaluation on liver fibrosis were reviewed in this article.

关 键 词：肝 纤维化 诊断显像 

分 类 号：R575.2[医药卫生—消化系统] R445[医药卫生—内科学]