NBI放大内镜对食管Barrett黏膜肠上皮化生的诊断价值分析  

Diagnostic Value of NBI Magnifying Endoscopy in Barrett Mucosa Intestinal Metaplasia of Esophagus

作　　者：周林华[1] 陈晓[2] 周昊[2] 段小峰 谢萍 蒋钰[1] ZHOU Lin-hua;CHEN Xiao;ZHOU Hao;DUAN Xiao-feng;XIE Ping;JIANG Yu(Yichun University,Yichun 336000,China;Yichun Vocational and Technical College,Yichun 336000,China;The People’s Hospital of Yichun City,Yichun 336000,China)

机构地区：[1]宜春学院,江西宜春336000 [2]宜春职业技术学院,江西宜春336000 [3]宜春市人民医院,江西宜春336000

出　　处：《宜春学院学报》2022年第3期45-48,共4页Journal of Yichun University

基　　金：江西省教育厅科技研究项目(编号:GJJ190854)。

摘　　要：目的:探究窄带谱成像(NBI)放大内镜技术对食管Barrett黏膜肠上皮化生临床诊断的应用价值。方法:将2018年4月到2021年4月收治入院的137例Barrett食管患者纳入本次研究的对象,先予以窄带谱成像(NBI)放大内镜技术检查,后在病变处靶向下取活检行病理检查,以病理检查结果为金标准,分析NBI放大内镜诊断食管Barrett黏膜肠上皮化生的临床价值。结果:NBI放大内镜诊断腺管开口Ⅳ型和Ⅴ型的患者,肠上皮化生检出率90.91%和100.00%,Ⅳ型和Ⅴ型肠上皮化生检出率高于Ⅰ~Ⅲ型,差异有统计学意义(χ^(2)=119.217,P<0.001);血管形态为4型和5型的患者,肠上皮化生检出率为91.67%和100.00%,4型和5型肠上皮化生检出率高于1~3型,差异有统计学意义(χ^(2)=119.217,P<0.001);以病理检查结果为金标准,NBI放大内镜诊断食管Barrett黏膜肠上皮化生的灵敏度为87.50%,特异度为92.56%。结论:窄带谱成像放大内镜技术能够提高Barrett食管黏膜肠上皮化生的检出率,对诊断Barrett食管黏膜肠上皮化生具有良好参考价值。Objective:To explore the clinical value of narrow band imaging(NBI)magnifying endoscopy in the diagnosis of esophageal Barrett mucosal intestinal metaplasia.Methods:A total of 137 patients with Barrett’s esophagus admitted from April 2018 to April 2021 were enrolled as the subjects of this study.First,narrowband imaging(NBI)magnifying endoscopy was performed.Then targeted biopsy was performed at the pathological site for pathological examination.Pathological examination results were taken as the gold standard to analyze the clinical value of NBI magnifying endoscopy in diagnosing Barrett mucosa intestinal metaplasia.Results:The detection rates of intestinal metaplasia were 90.91%and 100.00%in patients with typeⅣand typeⅤwith NBI magnifying endoscopy,respectively.The detection rate of intestinal metaplasia in typeⅣand typeⅤwere higher than that in typeⅠ~Ⅲ(χ^(2)=119.217,P<0.001).The detection rates of intestinal metaplasia in patients with vascular morphology type 4 and 5 were 91.67%and 100.00%,respectively.Meanwhile,the detection rates of intestinal metaplasia in patients with vascular morphology type 4 and 5 were higher than those in patients with vascular morphology type 1~3(χ^(2)=119.217,P<0.001).Using pathological examination results as the gold standard,the sensitivity and specificity of NBI magnifying endoscopy in the diagnosis of esophageal Barrett mucosal intestinal metaplasia were 87.50%and 92.56%,respectively.Conclusion:Narrowband imaging magnifying endoscopy could improve the detection rate of Barrett’s esophageal mucosal intestinal metaplasia.It has a good reference value for the diagnosis of Barrett’s esophageal mucosal intestinal metaplasia.

关 键 词：窄带谱成像 内镜技术 食管Barrett黏膜 肠上皮化生 

分 类 号：R571[医药卫生—消化系统]