乳酸的研究进展  

Research Progress of Lactic Acid

作　　者：陈为[1,2] 韩宛娜[1] 刘铎 金连海[1] CHEN Wei;HAN Wanna;LIU Duo;JIN Lianhai(Hypoxia and Health Medicine Research Center,Jilin Medical University,Jilin 132013;College of Medical,Yanbian University,Yanji 133002)

机构地区：[1]吉林医药学院低压低氧与健康医学研究中心,吉林132013 [2]延边大学医学院,延吉133002

出　　处：《吉林农业科技学院学报》2022年第3期19-22,共4页Journal of Jilin Agricultural Science and Technology University

基　　金：吉林省教育厅科研课题(JJKH20200457KJ);吉林省卫生健康青年科技骨干培养计划项目(2019Q033);吉林市科技创新发展计划项目(201830813)。

摘　　要：乳酸发现以来,一直被认为是糖酵解的副产品或废物,对机体具有多种损害。20世纪80年代,随着乳酸穿梭概念的提出,研究者对乳酸在新陈代谢中的理解发生了改变。近年来,越来越多的研究表明,乳酸不仅是一种能量来源,其在机体内的穿梭更是一种代谢缓冲剂或调节剂,乳酸还通过其受体发挥多功能信号分子作用,引起诸多生物学效应。本文结合近年来对乳酸的研究进行综述,以期为乳酸的研究提供理论依据。Since the discovery of lactic acid, it has been considered as a waste of glycolysis, which has a variety of damage to the body. In the 1980s, with the proposal of the concept of lactic acid shuttle,researchers’ understanding of lactic acid in metabolism changed revolutionarily. In recent years, more and more studies have shown that lactic acid is not only an energy source, but also a metabolic buffer or regulator. Lactic acid also plays a multifunctional signal molecule role through its receptor, causing many biological effects. This paper reviews the research on lactic acid in recent years, in order to provide a theoretical basis for the research of lactic acid.

关 键 词：乳酸 功能 研究进展 

分 类 号：Q591[生物学—生物化学]