Subthreshold laser systems:a narrative review of the current status and advancements for retinal diseases  

作　　者：Joshua Ong Amrish Selvam Dmitrii SMaltsev Xinyuan Zhang Lihteh Wu Jay Chhablani 

机构地区：[1]Department of Ophthalmology,University of Pittsburgh School of Medicine,Pittsburgh,Pennsylvania,USA [2]Department of Ophthalmology,Military Medical Academy,St.Petersburg,Russia [3]Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Tongren Hospital,Capital Medical University,Beijing,China [4]Macula,Vitreous and Retina Associates of Costa Rica,San José,Costa Rica [5]Illinois Eye and Ear Infirmary,Department of Ophthalmology,University of Illinois School of Medicine,Chicago,Illinois,USA

出　　处：《Annals of Eye Science》2022年第2期38-58,共21页眼科学年鉴（英文）

摘　　要：Background and Objective:Subthreshold laser therapy has emerged as a therapeutic alternative to traditional laser photocoagulation for certain ophthalmic diseases including central serous chorioretinopathy(CSCR),diabetic macular edema(DME),macular edema secondary to branch retinal vein occlusion(BRVO),and age-related macular degeneration(AMD).The objective of this paper is to review and discuss the clinical applications of subthreshold laser and the mechanisms of different subthreshold laser techniques including subthreshold micropulse laser(SMPL),selective retina therapy(SRT),subthreshold nanosecond laser(SNL),endpoint management(EpM),and transpupillary thermotherapy(TTT).Methods:A narrative review of English literature and publicly available information published before November 2021 from literature databases and computerized texts.We discuss the currently available subthreshold laser systems and the advancements made to perform different subthreshold laser techniques for various ophthalmic diseases.We highlight various clinical studies and therapeutic techniques that have been conducted to further understand the effectiveness of subthreshold laser in the clinical setting.We conclude the article by covering emerging subthreshold laser systems that are currently being developed for future clinical use.The PubMed database was utilized for peer-reviewed articles and pertinent information on subthreshold systems was cited from publicly available online websites covering specific systems.Key Content and Findings:Various subthreshold laser systems have been developed to treat certain retinal diseases.Several systems are currently in development for future clinical applications.Conclusions:While conventional laser photocoagulation has been effective in treating various retinal diseases,subthreshold laser systems aim to provide a therapeutic effect without visible signs of damage to the underlying tissue.This technology may be particularly effective in treating macular disorders.Further clinical studies are needed to e

关 键 词：Subthreshold laser micropulse laser RETINA central serous chorioretinopathy(CSCR) diabetic macular edema(DME) 

分 类 号：TN2[电子电信—物理电子学]