经颅直流电刺激治疗脑卒中后功能障碍的研究进展  

Research progress of transcranial direct current stimulation for post-stroke dysfunction

作　　者：邹文晨 朱璐 贾一颖 张志强[1,2] ZOU Wenchen;ZHU Lu;JIA Yiying;ZHANG Zhiqiang(Department of Rehabilitation,Shengjing Hospital of China Medical University,Shenyang,Liaoning 110134,P.R.China;The Second Clinical College of China Medical University,Liaoning 110122,P.R.China)

机构地区：[1]中国医科大学附属盛京医院康复医学中心,沈阳110134 [2]中国医科大学第二临床学院,沈阳110122

出　　处：《华西医学》2022年第5期668-673,共6页West China Medical Journal

基　　金：国家自然科学基金(82001485)。

摘　　要：经颅直流电刺激(transcranial direct current stimulation,t DCS)是利用恒定的低强度直流电(1~2 mA)调节大脑皮质神经元活动的非侵入性技术。近年来,tDCS作为探索人类大脑功能和治疗各种神经疾病的工具,受到越来越广泛的关注,但是tDCS治疗脑卒中后功能障碍这一领域,目前仍缺乏系统且全方位的总结。该文通过对tDCS治疗脑卒中后功能障碍进行阐述,综合近年来相关的基础研究和临床研究,总结并探讨tDCS治疗脑卒中后功能障碍的理论机制与应用效果,从而为更深层次的研究提供依据。Transcranial direct current stimulation(tDCS) is a non-invasive technique that uses constant lowintensity direct current(1 to 2 mA) to regulate neuronal activity in the cerebral cortex.In recent years,tDCS has received more and more attention as a tool to explore human brain function and treat various neurological diseases.However,there is still a lack of systematic and comprehensive reviews in the tDCS treatment of post-stroke dysfunction.This article reviews the treatment of post-stroke dysfunction with tDCS,integrates relevant basic research and clinical research in recent years,summarizes and discusses the theoretical mechanism and application effect of tDCS in the treatment of poststroke dysfunction,so as to provide a basis for further research.

关 键 词：经颅直流电刺激 脑卒中 功能障碍 运动功能障碍 认知障碍 

分 类 号：R743.3[医药卫生—神经病学与精神病学]