微创下置管抽吸液化引流手术治疗脑出血的临床效果探讨  

Clinical Effect of Minimally Invasive Aspiration and Liquefaction Drainage in the Treatment of Cerebral Hemorrhage

作　　者：蒙新宇 MENG Xin-yu(Department of Neurosurgery,Baodi District People's Hospital,Tianjin 301800,China)

机构地区：[1]天津市宝坻区人民医院神经外科,天津301800

出　　处：《医学信息》2022年第11期124-126,共3页Journal of Medical Information

摘　　要：目的探讨微创下置管抽吸液化引流手术治疗脑出血的临床效果。方法选择2020年4月-2021年4月天津市宝坻区人民医院神经外科收治的92例脑出血患者,依据随机数字表法分为对照组与观察组,各46例。对照组行小骨窗开颅血肿清除术治疗,观察组采用微创置管抽吸液化引流术治疗,比较两组血肿清除率、术后再出血率、降钙素原(PCT)、肿瘤坏死因子(TNF-α)、神经元特异性烯醇化酶(NSE)、并发症情况、神经功能及预后情况。结果观察组血肿清除率大于对照组,且术后再出血率小于对照组(P<0.05);两组PCT、TNF-α、NSE水平均低于治疗前,且观察组低于对照组(P<0.05);观察组术后并发症发生率低于对照组(P<0.05);观察组NIHSS评分低于对照组,SSS评分高于对照组(P<0.05);术后6个月,观察组GOS评分高于对照组,ADL评分低于对照组(P<0.05)。结论微创置管抽吸液化引流手术对脑出血患者具有良好的血肿清除效果,可降低其再出血风险及局部炎症反应,且术后并发症少,有利于患者神经功能及预后质量的改善。Objective To investigate the clinical effect of minimally invasive aspiration and liquefaction drainage in the treatment of cerebral hemorrhage.Methods Ninety-two patients with cerebral hemorrhage admitted to Department of Neurosurgery,Tianjin Baodi District People's Hospital from April 2020 to April 2021 were selected and divided into control group and observation group according to random number table method,with 46 cases in each group.The control group was treated with small bone window craniotomy for hematoma removal,and the observation group was treated with minimally invasive catheter aspiration and liquefaction drainage.The hematoma clearance rate,postoperative rebleeding rate,procalcitonin(PCT),tumor necrosis factor-α(TNF-α),neuron-specific enolase(NSE),complications,neurological function and prognosis were compared between the two groups.Results The hematoma clearance rate in the observation group was higher than that in the control group,and the postoperative rebleeding rate was lower than that in the control group(P<0.05).The levels of PCT,TNF-αand NSE in the two groups were lower than those before treatment,and those in the observation group were lower than the control group(P<0.05).The incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).The NIHSS score of the observation group was lower than that of the control group,and the SSS score was higher than that of the control group(P<0.05).At 6 months after operation,the GOS score of the observation group was higher than that of the control group,and the ADL score was lower than that of the control group(P<0.05).Conclusion Minimally invasive catheter suction liquefaction drainage surgery has good hematoma removal effect for patients with cerebral hemorrhage,which can reduce the risk of rebleeding and local inflammatory response,and has less postoperative complications,meawhileit’s conducive to the improvement of neurological function and prognosis quality of patients.

关 键 词：脑出血 微创置管抽吸液化引流 小骨窗开颅血肿清除术 神经功能 炎症反应 

分 类 号：R743[医药卫生—神经病学与精神病学]