顽固性口腔溃疡复发的危险因素分析  

Analysis of Risk Factors for the Relapse of Obstinate Oral Ulcer

作　　者：孙姣 SUN Jiao(Department of Stomatology,Shenyang 739 Hospital,Shenyang,Liaoning 110034,China)

机构地区：[1]沈阳七三九医院口腔科,辽宁沈阳110034

出　　处：《中国烧伤创疡杂志》2022年第3期225-228,共4页The Chinese Journal of Burns Wounds & Surface Ulcers

摘　　要：目的回顾性分析顽固性口腔溃疡复发的相关危险因素。方法选取2019年1月至2020年10月沈阳七三九医院收治的125例顽固性口腔溃疡患者作为研究对象,收集患者年龄、性别、是否饮酒、是否吸烟、是否喝茶、饮食类型、是否使用药物牙膏、牙刷毛硬度、刷牙次数、是否熬夜失眠、疲劳状态、心理状态、是否合并消化系统疾病等资料,根据口腔溃疡治愈后3个月是否再发口腔溃疡将患者分为复发组和未复发组,多因素Logistic回归分析顽固性口腔溃疡复发的相关危险因素。结果125例顽固性口腔溃疡患者愈后3个月再发口腔溃疡者32例,设为复发组;未再发口腔溃疡者93例,设为未复发组。多因素Logistic回归分析结果显示,年龄≥60岁、吸烟、饮食偏荤、使用药物牙膏、刷牙次数≤1次/天、熬夜失眠、疲劳、心理异常、合并消化系统疾病是顽固性口腔溃疡患者复发的独立危险因素(95%CI为1.016~1.134、1.003~1.164、1.001~1.397、1.024~1.364、1.029~1.413、1.019~1.433、1.027~1.389、1.041~1.397、1.024~1.369,P=0.011、0.046、0.048、0.022、0.021、0.030、0.021、0.013、0.022)。结论顽固性口腔溃疡的复发与患者的年龄、生活习惯、心理状态等多种因素密切相关。Objective To retrospectively analyze the risk factors associated with the relapse of obstinate oral ulcer.Methods 125 patients with obstinate oral ulcer,admitted into Shenyang 739 Hospital between January 2019 and October 2020,were selected as research subjects,and data of these subjects including age,sex,history of drinking alcohol,smoking and drinking tea,style of diet,use medicated toothpaste or not,hardness of toothbrush hairs,number of brushing teeth,stay up late and insomnia or not,state of fatigue,mental status,and with digestive system disorders or not.Based on whether oral ulcer reoccurred 3 months after oral ulcer healing,the subjects were divided into relapse group and non-relapse group.Multivariate Logistic regression analysis was conducted to analyze the relevant risk factors for the relapse of obstinate oral ulcer.Results Of the 125 patients with obstinate oral ulcer,32 cases developed ulcer relapse 3 months after oral ulcer healing,being set as relapse group,and the other 93 patients without the relapse of oral ulcer were set as non-relapse group.The results of multivariate Logistic regression analysis showed that age≥60 years old,smoking,having meat a lot,using medicated toothpaste,number of brushing teeth≤1 time/day,stay up late,fatigue,abnormal mental status and with digestive system disorders were the independent risk factors of the relapse of obstinate oral ulcer(95%CI:1.016-1.134,1.003-1.164,1.001-1.397,1.024-1.364,1.029-1.413,1.019-1.433,1.027-1.389,1.041-1.397,1.024-1.369,P=0.011,0.046,0.048,0.022,0.021,0.030,0.021,0.013,0.022).Conclusion The relapse of obstinate oral ulcer is closely associated with such factors as patients’age,life style and mental status.

关 键 词：顽固性口腔溃疡 复发 危险因素 LOGISTIC回归分析 

分 类 号：R781.5[医药卫生—口腔医学]