不同浓度阿托品治疗高度远视合并斜视患儿的效果  

Effects of different concentrations of Atropine in treatment of children with high hyperopia and strabismus

作　　者：吕自新 郑祥辉 姚晨阳 LYU Zixin;ZHENG Xianghui;YAO Chenyang(Department of Ophthalmology of Nanyang First People’s Hospital,Nanyang 473000 Henan,China;Nanyang Central Hospital,Nanyang 473000,Henan,China)

机构地区：[1]南阳市第一人民医院眼科,河南南阳473000 [2]南阳市中心医院,河南南阳473000

出　　处：《中国民康医学》2022年第9期51-53,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察不同浓度阿托品治疗高度远视合并斜视患儿的效果。方法:选取200例高度远视合并斜视患儿为研究对象,按照随机数字表法分为对照组和观察组各100例。对照组采用0.01%阿托品治疗,观察组采用0.1%阿托品治疗,比较两组疗效,治疗后屈光度差值、眼轴长度差值、眼压差值,不良反应发生率以及立视重建有效率。结果:观察组治疗总有效率为99.00%,高于对照组的92.00%,差异有统计学意义(P<0.05);治疗后,观察组屈光度差值、眼轴长度差值和眼压差值均高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为9.00%,高于对照组的1.00%,差异有统计学意义(P<0.05);观察组立视重建有效率为96.00%,高于对照组的82.00%,差异有统计学意义(P<0.05)。结论:0.1%阿托品治疗高度远视合并斜视患儿可提高治疗总有效率、屈光度差值、眼轴长度差值、眼压差值和立视重建有效率,其效果优于0.01%阿托品治疗,但不良反应发生率高于0.01%阿托品治疗。Objective:To observe effects of different concentrations of Atropine in treatment of children with high hyperopia and strabismus.Methods:200 children with high hyperopia and strabismus were selected as the research objects,and were divided into control group and observation group according to the random number table method,100 cases in each group.The control group was treated with 0.01% Atropine,while the observation group was treated with 0.1%Atropine.The curative effects,the diopter difference level,the axial length difference level,the intraocular pressure difference level,the incidence of adverse reactions and the effective rate of stereopsis reconstruction were compared between the two groups after the treatment.Results:The total effective rate of treatment in the observation group was 99.00%,which was higher than 92.00% in the control group,and the difference was statistically significant(P<0.05).After the treatment,the diopter difference level,the axial length difference level and the intraocular pressure difference level in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 9.00%,which was higher than 1.00% in the control group,and the difference was statistically significant(P<0.05).Further,the effective rate of stereoscopic reconstruction in the observation group was 96.00%,which was higher than 82.00% in the control group,and the difference was statistically significant(P<0.05).Conclusions:0.1% Atropine in the treatment of the children with high hyperopia and strabismus can improve the total effective rate of treatment,the diopter difference level,the axial length difference level and the intraocular pressure difference level and the effective rate of stereopsis reconstruction.Moreover,it is superior to 0.01%Atropine.However,the incidence of adverse reactions is also higher than 0.01%Atropine treatment.

关 键 词：阿托品 高度远视 斜视 患儿 不良反应 立视重建 屈光度 

分 类 号：R779.7[医药卫生—眼科]