DTI在脑卒中后假性延髓性麻痹吞咽障碍患者的研究进展  

Research progress of DTI in patients with swallowing disorder caused by pseudobulbar paralysis after stroke

作　　者：舒琳睿 孙道东[2] 周婷[2] 程红亮[2] 李静[2] 柳星 SHU Linrui;SUN Daodong;ZHOU Ting;CHENG Hongliang;LI Jing;LIU Xing(Anhui University of Traditional Chinese Medicine,Hefei 230000,China;The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei 230000,China)

机构地区：[1]安徽中医药大学,安徽合肥230000 [2]安徽中医药大学第二附属医院,安徽合肥230000

出　　处：《中国实用神经疾病杂志》2022年第3期381-385,共5页Chinese Journal of Practical Nervous Diseases

基　　金：安徽省重点研究和开发计划项目(编号:1804h08020288);安徽省针灸临床医学研究中心开放项目(编号:2021zjzx05);安徽省第十三批115产业创新团队“针药结合防治脑病创新团队”项目(编号:皖人才办[2020]4号);安徽省卫生健康委科研项目(编号:AHWJ2021a020)。

摘　　要：脑卒中后假性延髓性麻痹吞咽障碍是一种由脑卒中引起的以进食困难、饮水呛咳为主要表现的疾病,有较高的致死率和致残率。笔者对近年来有关脑卒中后假性延髓性麻痹吞咽障碍的弥散张量成像研究的文献进行检索并综述,发现吞咽困难与脑白质关系密切。大脑皮质的损伤后,皮质脑干束局部缺损,进而影响到吞咽功能,弥散张量成像能够作为一种对脑白质高度敏感的检查手段,可用来评估脑卒中后患者的脑白质损伤程度,为客观评估脑卒中后假性延髓性麻痹吞咽障碍提供影像学依据。Pseudobulbar paralysis swallowing disorder after stroke is a disease caused by stroke,which is mainly manifested by eating difficulty and drinking water choking cough.It has a high mortality and disability rate.The author searched and reviewed the literature on diffusion tensor imaging of dysphagia in pseudobulbar palsy after stroke in recent years,and found that dysphagia was closely related to cerebral white matter.After the injury of cerebral cortex,the local defect of cortical brainstem tract will affect the swallowing function.Diffusion tensor imaging can be used as a highly sensitive examination method for white matter,which can be used to evaluate the degree of white matter injury in patients after stroke,and provide imaging basis for objective evaluation of swallowing disorder in patients with pseudobulbar palsy after stroke.

关 键 词：脑卒中 吞咽障碍 脑白质 假性延髓性麻痹 弥散张量成像 

分 类 号：R743.3[医药卫生—神经病学与精神病学]