从“虚劳干血”探讨大黄[庶虫]虫丸治疗脑小血管病相关认知功能障碍  

Basis of Dahuang Zhechong pills in intervention of vascular cognitive impairment caused by cerebralsmall vessel disease via theory of“Xulao Ganxue”

作　　者：蔡君洁 梁静涛[2] 张勇[1] 何媛 常文 方妤[2] CAI Junjie;LIANG Jingtao;ZHANG Yong;HE Yuan;CHANG Wen;FANG Yu(Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China)

机构地区：[1]成都中医药大学,四川成都610075 [2]成都中医药大学附属医院,四川成都610072

出　　处：《陕西中医》2022年第6期759-762,共4页Shaanxi Journal of Traditional Chinese Medicine

基　　金：四川省科技厅重点研发项目(2021YFS0260);成都中医药大学附属医院基金资助项目(21ZL12)。

摘　　要：通过对脑小血管病相关认知功能障碍(CSVD-VCI)的病理变化和“虚劳干血”病机演化过程的分析,阐述“虚劳干血”在CSVD-VCI发病过程的作用,指出CSVD-VCI病位在脑络,病机为瘀血日久,干血阻络,疾病表现为脑腑虚劳状态,以认知功能下降为主要的临床症状。以“缓中补虚”为治则,其代表方剂大黄[庶虫]虫丸用于治疗早期CSVD-VCI,体现了“既病防变”的治疗思想及“异病同治”的辨证论治理念。Analysis of the pathological changes of vascular cognitive impairment caused by cerebral small vessel disease(CSVD-VCI)and the pathogenesis of Xulao Ganxue caused by consumptive disease.Elaborated crucial roles which the pathological changes of the Xulao Ganxue played in the disease process of CSVD-VCI.It is pointed out that CSVD-VCI disease is located in the brain collaterals.The pathogenesis is blood stasis for a long time and dry blood obstructs the collaterals.The disease is manifested as the fatigue of the brain,with the decline in cognitive function as the main clinical symptom.Establish the treatment principle of Huanzhong Buxu and use its representative prescription Dahuang Zhechong pill to intervene in the early stage of CSVD-VCI,which not only embodies the treatment idea of“Jibing Fangbian”in traditional Chinese medicine,but also embodies the concept of treatment based on syndrome differentiation of“Yibing Tongzhi”therapy.

关 键 词：脑小血管病 认知功能障碍 虚劳干血 大黄[庶虫]虫丸 络脉 

分 类 号：R743[医药卫生—神经病学与精神病学]