降血压治疗对脑血栓形成急性期患者NIHSS评分及预后的影响  

Effects of Hypotensive Therapy on NIHSS Score and Prognosis of Patients with Acute Cerebral Thrombosis

作　　者：陈晓祥 CHEN Xiaoxiang(Department of Neurology Second Ward,Juxian People's Hospital,Rizhao,Shandong Province,276500 China)

机构地区：[1]山东省日照市莒县人民医院神经内科二病区,山东日照276500

出　　处：《中外医疗》2022年第11期37-40,共4页China & Foreign Medical Treatment

摘　　要：目的探讨降血压治疗对脑血栓形成急性期患者美国国立卫生研究院卒中量表(NIHSS)评分及预后的影响。方法方便选取2018年4月—2020年4月该院治疗的脑血栓形成急性期患者84例,按随机数表法将其分为两组,各42例。对照组采用抗血小板聚集、抗凝及脱水等对症支持治疗,并积极预防并发症,观察组于常规对症支持治疗基础上采用降血压治疗。比较两组血压水平、NIHSS评分、生活质量及复发率。结果治疗后观察组收缩压(SBP)(126.69±8.41)mmHg、舒张压(DBP)(82.06±4.79)mmHg低于对照组,差异有统计学意义(t=6.034、4.501,P<0.05);两组治疗后NIHSS评分均较治疗前低,SF-36评分均较治疗前高,差异有统计学意义(P<0.05);观察组、对照组复发率(2.38%vs 7.14%)比较,差异无统计学意义(P>0.05)。结论脑血栓形成急性期患者采用降血压治疗能够降低血压水平,并不会增加对患者神经功能、生活质量及预后的影响,利于防止高血压对机体造成的危害。Objective To investigate the effect of hypotensive therapy on the score and prognosis of the National Institutes of Health Stroke Scale(NIHSS)in patients with acute cerebral thrombosis.Methods A total of 84 patients with acute cerebral thrombosis treated in the hospital from April 2018 to April 2020 were conveniently selected and divided into two groups according to the random number table method,with 42 cases in each group.The control group received anti-platelet aggregation,anticoagulation and dehydration and other symptomatic and supportive treatments,and actively prevented complications,while the observation group received blood pressure lowering therapy on the basis of routine symptomatic and supportive treatment.The blood pressure level,NIHSS score,quality of life and recurrence were compared between the two groups.Results After treatment,the systolic blood pressure(SBP)(126.69±8.41)mmHg and diastolic blood pressure(DBP)(82.06±4.79)mmHg in the observation group were lower than those in the control group,the difference was statistically significant(t=6.034,4.501,P<0.05).After treatment,the NIHSS scores in the two groups were lower than those before treatment,and the SF-36 scores were higher than those before treatment,the difference was statistically significant(P<0.05).There was no statistically significant difference in the recurrence rate between the observation group and the control group(2.38%vs 7.14%)(P>0.05).Conclusion In patients with acute cerebral thrombosis,hypotensive therapy can reduce the blood pressure level without increasing the influence on the neurological function,quality of life and prognosis of the patients,and it is beneficial to prevent the harm caused by hypertension to the body.

关 键 词：脑血栓形成 急性期 降血压治疗 神经功能 血压水平 生活质量 复发率 

分 类 号：R743.32[医药卫生—神经病学与精神病学]