椎动脉支架成形术和药物治疗椎动脉动脉粥样硬化狭窄的效果分析  

Analysis of the Effect of Vertebral Artery Stenting and Drugs in the Treatment of Vertebral Artery Atherosclerotic Stenosis

作　　者：严明[1] 徐红[1] 徐小军[1] YAN Ming;XU Hong;XU Xiaojun(Department of Neurology,Jingjiang People's Hospital,Jingjiang,Jiangsu Province,214500 China)

机构地区：[1]靖江市人民医院神经内科,江苏靖江214500

出　　处：《中外医疗》2022年第6期46-49,共4页China & Foreign Medical Treatment

摘　　要：目的研究椎动脉支架成形术和药物治疗椎动脉动脉粥样硬化狭窄的效果。方法方便选择该院2018年1月—2021年6月收治的椎动脉动脉粥样硬化狭窄患者72例作为该次研究对象,根据治疗方法差异分为研究组与对照组,每组36例。对照组采用药物治疗,研究组采用椎动脉支架成形术治疗,对比两组患者治疗前后的脑血流量指标、神经功能恢复情况以及生活质量改善情况。结果治疗前两组的脑血流量指标比较,差异无统计学意义(P>0.05);治疗后,研究组rCBF(0.98±0.11)mL/(g·min)、rMTT(1.03±0.04)mL/(g·min)、rTTP(1.01±0.12)s均优于对照组相关指标,差异有统计学意义(t=4.440、14.145、5.529,P<0.05),研究组rCBV(1.04±0.16)s与对照组rCBV(1.03±0.14)s比较,差异无统计学意义(t=0.282,P>0.05)。治疗前,两组神经功能评分比较,差异无统计学意义(P>0.05);治疗后研究组神经功能评分(10.02±3.39)分,优于对照组的(13.94±3.47)分,差异有统计学意义(t=4.848,P<0.05)。治疗前,两组的生活质量比较,差异无统计学意义(P>0.05);治疗后研究组生理健康(85.49±6.84)分、心理状态(87.53±5.28)分、独立能力(88.19±9.31)分、社会关系(90.28±7.42)分,均优于对照组,差异有统计学意义(t=2.714、3.485、2.474、2.477,P<0.05)。结论采用椎动脉支架成形术治疗椎动脉动脉粥样硬化狭窄具有更加理想的效果,患者临床症状显著减轻,脑血流量指标得到明显的改善,值得在临床中推广应用。Objective To study the effects of vertebral artery stenting and drugs in the treatment of vertebral artery atherosclerotic stenosis.Methods 72 patients with atherosclerotic stenosis of the vertebral artery admitted to the hospital from January 2018 to June 2021 were conveniently selected as the subjects of this study.According to the difference of treatment methods,they were divided into study group and control group,with 36 cases in each group.The control group was treated with drugs,and the study group was treated with vertebral artery stenting.The cerebral blood flow indexes,the recovery of nerve function and the improvement of the quality of life of the two groups of patients before and after treatment were compared.Results Before treatment,there was no statistically significant difference in cerebral blood flow indexes between the two groups(P>0.05);after treatment,the study group's rCBF(0.98±0.11)mL/(g·min),rMTT(1.03±0.04)mL/(g·min)and rTTP(1.01±0.12)s were better than the related indicators of the control group,the difference was statistically significant(t=4.440,14.145,5.529,P<0.05),compared with the rCBV(1.04±0.16)s of the study group and the control group(1.03±0.14)s,the difference was not statistically significant(t=0.282,P>0.05).Before treatment,there was no statistically significant difference between the two groups of neurological function scores(P>0.05);after treatment,the neurological function score of the study group was(10.02±3.39)points,which was better than that of the control group(13.94±3.47)points,and the difference was statistically significant(t=4.848,P<0.05).Before treatment,there was no statistically significant difference in the quality of life between the two groups(P>0.05);after treatment,the study group had physical health(85.49±6.84)points,mental state(87.53±5.28)points,independent ability(88.19±9.31)points and social relations(90.28±7.42)points were better than those of the control group,and the difference was statistically significant(t=2.714,3.485,2.474,2.477,P<0.05

关 键 词：椎动脉支架成形术 药物治疗 椎动脉动脉粥样硬化狭窄 脑血流量指标 

分 类 号：R743[医药卫生—神经病学与精神病学]