微波消融治疗胆肠吻合术后肝脏恶性肿瘤术前肠道准备及应用抗生素对降低术后并发症的效果  

Effects of bowel preparation combined with antibiotics before microwave ablation of liver malignancies after biliary-enteric anastomosis for reducing incidence and severity of complications

作　　者：李昀霖 谭水莲 于晓玲 梁萍 姚俊东 程志刚 韩治宇 刘方义 于杰 LI Yunlin;TAN Shuilian;YU Xiaoling;LIANG Ping;YAO Jundong;CHENG Zhigang;HAN Zhiyu;LIU Fangyi;YU Jie(Medical School of Chinese PLA, Beijing 100853, China;Department of Interventional Ultrasound, the Fifth Medical Centre, Chinese PLA General Hospital, Beijing 100853, China)

机构地区：[1]解放军医学院,北京100853 [2]中国人民解放军总医院第五医学中心介入超声科,北京100853

出　　处：《中国介入影像与治疗学》2022年第6期329-332,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：国家自然科学基金(82172027)。

摘　　要：目的观察超声引导下微波消融(MWA)治疗胆肠吻合术(BEA)后肝脏恶性肿瘤术前肠道准备及应用抗生素对降低术后并发症及其严重程度的价值。方法回顾性分析31例接受超声引导下MWA的BEA后肝脏恶性肿瘤患者,其中17例MWA前接受(A组)、14例(B组)未接受肠道准备及应用抗生素,对比观察2组术后并发症发生率及严重程度。结果2组患者基线特征及原发肿瘤类型差异均无统计学意义(P均>0.05)。31例均顺利完成MWA。MWA后A组住院时间、发热率、发热持续时间、菌血症发生率及肝脓肿发生率均低于B组(P均<0.05)。结论MWA治疗BEA后肝脏恶性肿瘤患者术前肠道准备及合理应用抗生素可明显降低术后并发症发生率及严重程度。Objective To observe the value of bowel preparation combined with application antibiotics before ultrasound-guided microwave ablation(MWA)of liver malignancies for reducing the incidence and severity of complications after biliary-enteric anastomosis(BEA).Methods Data of 31 patients with liver malignancies after BEA biliary-enteric anastomosis and underwent ultrasound-guided MWA were retrospectively analyzed.The patients were divided into group A(with bowel preparation combined with antibiotics before MWA,n=17)and group B(no bowel preparation nor antibiotics before MWA,n=14).The incidence and severity of complications were observed and compared between groups.Results MWA of liver malignancy was successfully completed in all 31 patients.There was no significant difference of baseline characteristics nor primary tumor types between groups(all P>0.05).The hospitalization time,fever rate,fever duration,the incidence of bacteremia and liver abscess after MWA in group A were lower than those in group B(all P<0.05).Conclusion Bowel preparation combined with reasonable antibiotics could obviously reduce the incidence and severity of complications of MWA for treating liver malignancies in patients after BEA.

关 键 词：肝肿瘤 胆管肠吻合术 肝 肠道准备 抗生素 肝脓肿 并发症 超声检查 微波消融 

分 类 号：R735.7[医药卫生—肿瘤] R815[医药卫生—临床医学]