Corneal transplantation outcomes after the extrusion of an intrastromal keratoprosthesis:a pilot study  

作　　者：Chiara Fariselli Ibrahim Toprak Olena Al-Shymali Jorge L.Alio del Barrio Jorge L.Alio 

机构地区：[1]Research and Development Department,Calle Cabaiial,1 Edificio Vissum,03016 Alicante,Spain [2]Department of Ophthalmology,Pamukkale University,Denizli,Turkey [3]Cornea and Refractive Surgery Department,Calle Cabanal,1 Edificio Vissum,03016 Alicante,Spain [4]Division of Ophthalmology,Universidad Miguel Hernandez,Alicante,Spain

出　　处：《Eye and Vision》2022年第2期36-40,共5页眼视光学杂志（英文）

基　　金：This publication has been carried out in the framework of the Red Tematica de Investigacion Cooperativa en Salud(RETICS),referenee number RD 16/0008/0012,financed by the Instituto Carlos Ⅲ-General Subdirection of Networks and Cooperative Investigation Centers(R&D&I National Plan 2008-2011)and the Euro pea n Regional Developme nt Fund(Fondo Europeo de Desarrollo Regional FEDER).

摘　　要：This short report includes 5 eyes of 5 patients(mean age 63.2±12 years)who underwent a tectonic keratoplasty[deep anterior lamellar keratoplasty(DALK)or penetrating keratoplasty(PK)]in order to rehabilitate the eye after the extrusion of the non-perforating keratoprosthesis(Kpro)KeraKlear(KeraMed,USA).The non-perforating Kpro was extruded after a mean period of 21.4±21.8 months due to melting.In two cases,the keratoplasty was performed the same day of the non-perforating Kpro removal due to a severe melting,while in the other three cases it was performed 1 to 3 months later.Two eyes received a DALK,but in 3 eyes a macroscopic Descemetzs membrane perforation forced the conversion into a PK.The mean follow-up period after the keratoplasty was 16.8±6.6 months.No cases of rejection were recorded.All the 5 eyes achieved"anatomical success"(transparent graft,with no signs of infection or inflammation).Two eyes showed limited functional success"because the achievement of the best visual potential was prevented by the development of glaucomatous optic atrophy during the follow-up period.In conclusion,this short report presents an unexpected success of a keratoplasty performed with a tectonic purpose after the extrusion of the non-perforating Kpro because the corneal graft remained transparent,without neovascularization or scarring during the follow-up period.This initial evidence shows some encouraging results reg a rd i ng graft survival rate and the achievement of a useful visual rehabilitation with keratoplasty after a nonperforating Kpro failure in stead of repeating the Kpro implantation.

关 键 词：KERATOPROSTHESIS EXTRUSION KERATOPLASTY Comeal transplantation 

分 类 号：R779.65[医药卫生—眼科]