磁共振水脂分离mDixon技术对胸腺瘤、胸腺增生和胸腺囊肿的鉴别诊断  

Differential Diagnosis of m Dixon Magnetic Resonance Imaging Among Thymoma,Thymus Hyperplasia and Thymic Cyst

作　　者：杨晶[1,2] 高艳 单艺[1,2] 李琼阁 赵澄[1,2] 卢洁 YANG Jing;GAO Yan;SHAN Yi;LI Qiongge;ZHAO Cheng;LU Jie(Department of Radiology and Nuclear Medicine,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院放射与核医学科,北京100053 [2]磁共振成像脑信息学北京市重点实验室,北京100053

出　　处：《中国医学影像学杂志》2022年第5期465-468,共4页Chinese Journal of Medical Imaging

摘　　要：目的通过计算信号强度指数(SⅡ)探讨MRI水脂分离mDixon技术对胸腺瘤、胸腺增生和胸腺囊肿的鉴别诊断。资料与方法前瞻性纳入2017年1月—2020年1月首都医科大学宣武医院32例胸腺占位患者,以术后病理结果为“金标准”,共41个胸腺占位分为3组:胸腺瘤组20例,胸腺增生组13例,胸腺囊肿8例。采用3.0T MR扫描仪进行T2fs成像和T1m Dixon成像,得到正反相位,水相和脂相。对3组患者的T2fs和T1正反相位图像进行主观评价。测量3组患者胸腺病变的信号强度,计算SⅡ,并比较组间差异。结果胸腺瘤、胸腺增生和胸腺囊肿3组病例T2fs均呈高信号,在T1正反相位图像上信号缺失不等,视觉评价很难鉴别;3组病例的SⅡ分别为3.15(-8.45,7.93)%、44.48(38.07,44.49)%和-6.96(-35.06,15.67)%,3组间差异有统计学意义(H=22.422,P=0.000);胸腺瘤和胸腺增生、胸腺增生和胸腺囊肿两者之间差异有统计学意义(P=0.000,P<0.001),胸腺瘤与胸腺囊肿之间差异无统计学意义(P=1.000)。结论MRI mDixon技术通过计算SⅡ可以为胸腺增生和胸腺瘤、胸腺增生和胸腺囊肿之间的鉴别诊断提供帮助。Purpose To investigate the differential diagnosis of mDixon MRI among thymoma,thymus hyperplasia and thymic cyst by calculating the signal intensity index(SII).Materials and Methods According to postoperative pathological results,32 patients with 41thymus masses in Xuanwu Hospital,Capital Medical University from January 2017 to January 2020 were divided into thymoma group(n=20),thymus hyperplasia group(n=13)and thymic cyst group(n=8).T2-weighted fat-suppressed sequence(T2fs)and T1 mDixon sequence were performed using a 3.0T magnetic resonance scanner to obtain in-phase and out-phases images,water and lipid images at the same time.The SII of thymus masses on in-phase and out-phases images were measured and calculated.The statistical differences among the groups were compared.Results High signal intensity on T2fs(fat suppression)was presented in all the three groups of thymoma,thymic hyperplasia and thymic cyst,with different signal loss on T1 in-phase and out-phases images,which were difficult to be differentiated by visual evaluation.The median SII of lesions in thymic tumor,thymus hyperplasia and thymic cyst groups were 3.15(-8.45,7.93)%,44.48(38.07,44.49)%and-6.96(-35.06,15.67)%,with statistical difference(H=22.422,P=0.000),respectively.The difference between thymoma and thymus hyperplasia was statistically significant(P=0.000),as well as the difference between thymus hyperplasia and thymic cyst(P<0.001).There was no statistical significance on the difference between thymoma and thymic cyst(P=1.000).Conclusion MRI mDixon technique can provide help for the differential diagnosis of thymic hyperplasia and thymoma,thymic hyperplasia and thymic cyst by calculating SII.

关 键 词：胸腺瘤 胸腺增生 胸腺肿瘤 磁共振成像 诊断 鉴别 

分 类 号：R736.3[医药卫生—肿瘤] R445.2[医药卫生—临床医学]