利多卡因复合达克罗宁胶浆预处理在无痛胃镜检查中的应用  

Application of Lidocaine Combined with Dyclonine Mucilage Pretreatment in Painless Gastroscopy

作　　者：黄小贤[1] 张欢楷[1] 张隆盛[1] 程卫杰[1] 林楚玉[1] 林荣凯[1] Huang Xiaoxian(Jieyang people's Hospital,Jieyang Guangdong 522000)

机构地区：[1]揭阳市人民医院,广东揭阳522000

出　　处：《黑龙江医药》2022年第3期509-512,共4页Heilongjiang Medicine journal

基　　金：揭阳市卫生医疗类项目(编号:YLWS025、YLWS031)。

摘　　要：目的:探讨利多卡因复合达克罗宁胶浆预处理在无痛胃镜检查中的应用效果。方法:选择2019年5月至2021年5月在我院接受无痛胃镜检查患者80例,随机分为预处理组(T组)和对照组(C组),每组40例。T组患者在检查前10min口服达克罗宁胶浆10mL,嘱患者咽喉部含服1min后再缓慢吞下,随后静脉注射利多卡因0.5mg/kg,C组患者在检查前10min口服西甲硅油10mL。两组患者随后在丙泊酚麻醉下行胃镜检查。记录两组患者检查过程生命体征变化情况,包括检查前、检查中、检查后的平均动脉压和心率变化情况;记录两组患者丙泊酚注射痛发生例数、丙泊酚使用总量、完全苏醒时间;记录两组患者呼吸抑制、体动反应、呛咳等不良反应发生情况。结果:T组患者胃镜检查时间明显低于C组(P<0.05),T组患者检查中平均动脉压、心率明显高于C组(P<0.05),T组患者丙泊酚注射痛发生例数、丙泊酚使用总量、完全苏醒时间明显低于C组(P<0.05),T组患者不良反应发生情况明显低于C组(P<0.05)。结论:利多卡因复合达克罗宁胶浆预处理用于无痛胃镜检查时,患者血流动力学更加平稳,注射痛发生率低,不良反应少,减少丙泊酚使用量,缩短完全苏醒时间,提高胃镜检查时舒适度,值得推广。Objective:The purpose of this study was to investigate the application effect of lidocaine combined with dyclonine mucilage pretreatment in painless gastroscopy. Methods:Eighty patients with painless gastroscopy in our hospital were selected and randomly divided into group T and group C,40 cases in each group. The patients in group T took 10 mL of dyclonine mucilage orally 10 min before the examination, and were instructed to swallow it slowly after 1 min in throat.Then lidocaine 0.5 mg/kg was injected intravenously in group T. The patients in group C took 10 mL of simethicone orally 10 min before the examination. Two groups of patients were followed by gastroscopy under propofol anesthesia. The changes of vital signs in the two groups were recorded, including the changes of mean arterial pressure and heart rate before, during and after the examination.The number of patients with propofol injection pain, the total dosage of propofol and the time of complete recovery were recorded.The adverse reactions such as respiratory depression, body movement reaction and cough were recorded. Results:The time of gastroscopy in group T was significantly lower than that in group C(P<0.05). The mean arterial pressure and heart rate in group T were significantly higher than those in group C(P<0.05). The number of cases of propofol injection pain, the total amount of propofol used and the complete recovery time in group T were significantly lower than those in group C(P<0.05). The incidence of adverse reactions in group T was significantly lower than that in group C(P<0.05). Conclusion:Lidocaine combined with dyclonine mucilage pretreatment for painless gastroscopy, patients with more stable hemodynamics, low incidence of injection pain, less adverse reactions, reduce the use of propofol, shorten the complete recovery time, improve the comfort of gastroscopy, it is worth promoting.

关 键 词：利多卡因 达克罗宁 无痛胃镜检查 舒适化医疗 

分 类 号：R573[医药卫生—消化系统]