Nonfunctional pancreatic neuroendocrine tumours misdiagnosed as autoimmune pancreatitis:A case report and review of literature  

作　　者：Zi-Qi Lin Xin Li Yan Yang Yi Wang Xiao-Ying Zhang Xiao-Xin Zhang Jia Guo 

机构地区：[1]Department of Integrated Traditional Chinese and Western Medicine,Sichuan Provincial Pancreatitis Centre and West China-Liverpool Biomedical Research Centre,West China Hospital,Sichuan University,Chengdu610041,Sichuan Province,China [2]Laboratory Medicine,West China School of Medicine,Sichuan University,Chengdu 610041,Sichuan Province,China [3]Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China

出　　处：《World Journal of Clinical Cases》2022年第15期4886-4894,共9页世界临床病例杂志

基　　金：Supported by National Natural Scientific Foundation of China,No.8150341 to Lin ZQ,and No.81873107 to Guo J.

摘　　要：BACKGROUND Nonfunctional pancreatic neuroendocrine tumours are difficult to diagnose in the early stage of disease due to a lack of clinical symptoms,but they can rarely manifest as autoimmune pancreatitis.Autoimmune pancreatitis is an uncommon disease that may cause recurrent acute pancreatitis and is therefore often regarded as a special type of chronic pancreatitis.CASE SUMMARY We report a case of a 42-year-old female who had nonspecific upper abdominal pain for 4 years and radiological abnormalities of the pancreas that mimicked autoimmune pancreatitis.The symptoms and pancreatic imaging did not improve following 1 year of steroid therapy.Finally,pancreatic biopsy was performed through endoscopic ultrasonography-guided fine-needle aspiration biopsy,and nonfunctional pancreatic neuroendocrine tumours were ultimately diagnosed.Pancreatectomy has resolved her symptoms.CONCLUSION Therefore,the differentiation of nonfunctional pancreatic neuroendocrine tumours from autoimmune pancreatitis is very important,although it is rare.We propose that endoscopic ultrasonography-guided fine-needle aspiration biopsy should be performed if imaging characteristics are equivocal or the diagnosis is in question.

关 键 词：Pancreatic neuroendocrine tumour Nonfunctional pancreatic neuroendocrine tumour Autoimmune pancreatitis Endoscopic ultrasonography-guided fine needle aspiration biopsy Case report 

分 类 号：R735.9[医药卫生—肿瘤]