The prevention role of Spirulina platensis(Arthrospira platensis)on intestinal health  

作　　者：Ender Deniz Asmaz Nilay Seyidoglu 

机构地区：[1]Department of Histology and Embryology,Veterinary Faculty,Bursa Uludag University,Nilufer 16059,Turkey [2]Department of Physiology,Veterinary Faculty,Tekirdag Namik Kemal University,Suleymanpasa 59030,Turkey

出　　处：《Food Science and Human Wellness》2022年第5期1342-1346,共5页食品科学与人类健康（英文）

基　　金：supported by grant from the Research Foundations of University(NKUBAP.10.GA.16.074)。

摘　　要：Spirulina is a popular herbal food that has a preventive effect on health.In the study,it aimed to evaluate the effects of different doses of Spirulina platensis(Arthrospira platensis)on the morphological properties of the duodenum of rats,and to assign the effect of Spirulina on the expression of proliferating cell nuclear antigen(PCNA)in the rat duodenum,and thereby to observe the effects on intestinal health.30 male Wistar albino rats were divided into 3 groups for 45 days.The first group was received the basal diet;the second group was given 500 mg/kg Spirulina daily by oral gavage;the third group was given 1000 mg/kg Spirulina daily.The duodenum segments were taken at the end of the trial and processed for histological assay.Although the total mucosa,villus height and villus/cript ratio were found higher in high dose Spirulina,the lower cript depth was detected in same group compared to control and low dose group.A significant increase was observed at high dose compared to the control and low dose group in terms of PCNA expression intensity and proliferation index.Findings suggest that high dose of Spirulina may support the duodenal growth,and thereby intestinal health.

关 键 词：HISTOCHEMISTRY DUODENUM Spirulina platensis Intestinal health 

分 类 号：TS254.58[轻工技术与工程—水产品加工及贮藏工程] S816.7[轻工技术与工程—食品科学与工程]