胃镜活检对胃部高级别上皮内瘤变的诊断价值  

Diagnostic value of gastroscopic biopsy in gastric high-grade intraepithelial neoplasia

作　　者：吴琪[1] 赵文星[2] WU Qi;ZHAO Wenxing(Department of Histology and Embryology,Heze Medical College,Shandong Province,Heze274000,China;Department of Clinical Medicine,Heze Medical College,Shandong Province,Heze274000,China)

机构地区：[1]菏泽医学专科学校组织胚胎学教研室,山东菏泽274000 [2]菏泽医学专科学校临床医学系,山东菏泽274000

出　　处：《中国当代医药》2022年第15期112-114,共3页China Modern Medicine

基　　金：山东省医药卫生科技发展计划项目(2018WS495)。

摘　　要：目的探讨胃镜活检对胃部高级别上皮内瘤变的诊断价值。方法选取2018年8月至2021年8月菏泽医学专科学校附属医院收治的82例确诊为胃部高级别上皮内瘤变患者作为研究对象,以手术病理切片检查为金标准,分析胃镜活检检查早期胃部高级别上皮内瘤变阳性检出率、发展期胃部高级别上皮内瘤变阳性检出率、总胃部高级别上皮内瘤变阳性检出率,并计算胃镜与手术病理切片的一致性。结果胃镜活检检查早期胃部高级别上皮内瘤变的阳性检出率为50.00%(41/82)、发展期胃部高级别上皮内瘤变阳性检出率为47.56%(39/82)、总胃部高级别上皮内瘤变阳性检出率为97.56%(80/82),与手术病理切片检查[51.22%(42/82)、48.78%(40/82)、100.00%(82/82)]比较,差异无统计学意义(P>0.05)。接受胃镜活检诊断胃部高级别上皮内瘤变与手术病理切片的一致性经检验Kappa=0.833,一致性较好。结论胃部高级别上皮内瘤变患者接受胃部活检检查后,结果与手术病理切片检查结果一致,临床诊断价值高,值得推荐。Objective To investigate the diagnostic value of gastroscopic biopsy in gastric high-grade intraepithelial neoplasia.Methods A total of 82 patients diagnosed with gastric high-grade intraepithelial neoplasia who were admitted to the Affiliated Hospital of Heze Medical College from August 2018 to August 2021 were selected as the research subjects.The positive detection rate of early gastric high-grade intraepithelial neoplasia,developmental gastric high-grade intraepithelial neoplasia and total gastric high-grade intraepithelial neoplasia were analyzed using surgical pathological biopsy as the gold standard,and the consistency between gastroscopy and surgical pathological biopsy was calculated.Results The positive rate of early gastric high-grade intraepithelial neoplasia was 50.00%(41/82),that of developing gastric high-grade intraepithelial neoplasia was 47.56%(39/82),and that of total gastric high-grade intraepithelial neoplasia was 97.56%(80/82).There were no significant differences compared with surgical pathology(51.22%[42/82],48.78%[40/82],100.00%[82/82]).The consistency between the diagnosis of high-grade intraepithelial neoplasia of the stomach by gastroscopy biopsy and the surgical pathological section was tested with Kappa=0.833,indicating a good consistency.Conclusion The results of gastric biopsy in patients with gastric high-grade intraepithelial neoplasia are consistent with the results of surgical pathological biopsy,and the clinical diagnostic value is high,which is worthy of recommendation.

关 键 词：胃部高级别上皮内瘤变 胃镜活检 手术病理切片检查 阳性检出率 敏感度 特异度 

分 类 号：R735.2[医药卫生—肿瘤]