超声对导管型乳腺癌与导管内乳头状瘤患者的诊断价值  

Differential diagnosis of ductal breast cancer and intraductual papilloma by ultrasonography

作　　者：崔红 刘沅林[2] 陈亮 CUI Hong;LIU Yuanlin;CHEN Liang(Department of Ultrasound,Hai'an People's Hospital,Hai'an 226600,China;Department of Obstetrics and Gynecology,Affiliated Hospital of Nantong University,Nantong 226001,China)

机构地区：[1]海安市人民医院超声科,江苏海安226600 [2]南通大学附属医院妇产科,江苏南通226001

出　　处：《分子影像学杂志》2022年第3期404-407,共4页Journal of Molecular Imaging

基　　金：南通市级课题(MS2017013-1)。

摘　　要：目的 探讨超声对导管型乳腺癌(DBC)与导管内乳头状瘤(IDP)患者的鉴别诊断。方法本研究为回顾性研究,以我院2017年1月~2020年12月收治的110例乳腺疾病患者作为研究对象,其中DBC患者59例,IDP患者51例,分析两组患者的常规超声、超声血流情况之间的差异,分析及Logistic回归诊断模型。结果IDP以及DBC患者的导管形态(χ^(2)=25.69.2,P<0,001)、导管走行(χ^(2)=20.321,P<0.001)、导管壁回声(χ^(2)=6.052,P=0.014)及钙化灶情况(χ^(2)=34.552,P<0.001)的差异有统计学意义,两组患者的血流分布之间的差异有统计学意义(χ^(2)=22.441,P<0.001),但两组血流分级之间的差异无统计学意义(P>0.05);通过多因素分析,患者的导管、导管走行、导管壁回声、钙化、血流分布均是DBC诊断的重要因素。结论超声对DBC与IDP患者具有较强的鉴别诊断意义,导管增粗、导管走行不规则、导管壁回声不清晰、钙化不明显、血流分布均是DBC诊断的重要依据。Objective To explore the differential diagnosis between ductal breast cancer(DBC) and intraductual papilloma(IDP)by ultrasonography.Methods This retrospective study enrolled 110 patients with breast diseases treated in our hospital from January 2017 to December 2020.These patients included 59 patients with DBC and 51 patients with IDP.The differences of the routine ultrasound features and ultrasound blood flow between the two groups were compared.The logistic regression diagnostic model was analyzed.Results There were significant differences in the catheter morphology(χ^(2)=25.692,P<0.001),catheter running(χ^(2)=20.321,P<0.001),catheter wall echo(χ^(2)=6.052,P=0.014),calcification foci(χ^(2)=34.552,P<0.001) and blood flow distribution(χ^(2)=22.441,P<0.001) between patients with IDP and DBC,while there was no significant difference in blood flow grade between the two groups(P>0.05).Through multivariate analysis,the patient’s catheter,catheter running,catheter wall echo,calcification foci and blood flow distribution were important factors in the diagnosis of DBC.Conclusion Ultrasound has good differential diagnostic significance for patients with DBC and IDP.The thickening of catheter,irregular routing of catheter,unclear echo of catheter wall,unclear calcification foci and blood flow distribution are the important basis for the diagnosis of DBC.

关 键 词：导管型乳腺癌 导管内乳头状瘤 超声 鉴别诊断 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]