食管贲门癌患者术后发生急性呼吸衰竭的影响因素  

Analysis of Factors Affecting the Postoperative Acute Respiratory Failure in Patients with Esophageal Cardiac Cancer

作　　者：孙克 赵海艳 张宏玲 胡淑敏 SUN Ke;ZHAO Haiyan;ZHANG Hongling(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2022年第6期930-932,共3页The Practical Journal of Cancer

基　　金：河南省医学科技攻关计划(编号:201901035)。

摘　　要：目的 探讨食管贲门癌患者术后发生急性呼吸衰竭(ARF)的影响因素。方法 回顾性分析247例食管癌、贲门癌患者的临床资料,所有患者均顺利完成手术。根据患者术后是否发生ARF分为发生组与未发生组,统计2组临床资料,分析食管贲门癌患者术后发生ARF的影响因素。结果 247例食管癌、贲门癌患者中,术后有21例发生ARF,发生率为8.50%(21/247)。发生组有吸烟史、术前肺功能异常、合并糖尿病、术前合并肺部合并症、手术时间≥3 h、术后合并其他并发症的患者占比均高于未发生组,差异有统计学意义(P<0.05);2组性别、年龄、术中气胸对比,差异无统计学意义(P>0.05)。Logistic回归分析:吸烟史、术前肺功能异常、合并糖尿病、术前合并肺部合并症、手术时间≥3 h、术后合并其他并发症是食管贲门癌患者术后发生ARF的独立危险因素(P<0.05且OR≥1)。结论 食管贲门癌患者术后ARF发生较高,吸烟史、术前肺功能异常、合并糖尿病、术前合并肺部合并症、手术时间≥3 h、术后合并其他并发症是其独立危险因素,临床应予以高度重视。Objective To investigate the influencing factors of postoperative acute respiratory failure(ARF) in patients with esophageal cardiac cancer.Methods The clinical data of 247 patients with esophageal and cardia cancer were retrospectively analyzed,and all patients completed the operation successfully.According to whether ARF occurred after surgery was divided into occurrence and untreated groups,the clinical data of the 2 groups were counted,and the influencing factors of ARF in patients with esophageal cardia cancer were analyzed.Results Of 247 patients with esophageal and cardiac cancer,21 developed ARF with an incidence of 8.50%(21/247).The history of smoking,preoperative pulmonary function,diabetes,preoperative pulmonary complications,3 h,and the proportion of other complications were higher than none,respectively(P<0.05),sex,age and thorax(P>0.05).Logistic regression analysis:smoking history,preoperative abnormal pulmonary function,diabetes mellitus,preoperative pulmonary complications and pulmonary comorbidities,3 h,and other postoperative complications were independent risk factors for postoperative ARF in patients with esophageal cardia cancer(P<0.05 and OR 1).Conclusion High postoperative ARF in esophageal cardia cancer,smoking history,preoperative abnormal lung function,diabetes,preoperative pulmonary complications,surgical time of 3 h and other postoperative complications are independent risk factors,which should be paid great clinical attention.

关 键 词：食管贲门癌 术后急性呼吸衰竭 影响因素 

分 类 号：R735.1[医药卫生—肿瘤]