某院门诊儿童常用药品说明书中儿童用药信息标注情况调查分析  

Investigation on Annotation of Children’s Medication Information in Instructions of Commonly Used Drugs for Children in Outpatients of a Hospital

作　　者：郭志烨 李玲玲 褚智君 张晓旭[1] 齐会红 周航 缴万里[1] Guo Zhiye;Li Lingling;Chu Zhijun;Zhang Xiaoxu;Qi Huihong;Zhou Hang;Jiao Wanli(Tangshan Gongren Hospital,Hebei Tangshan 063000,China)

机构地区：[1]唐山市工人医院,河北唐山063000

出　　处：《儿科药学杂志》2022年第6期33-37,共5页Journal of Pediatric Pharmacy

基　　金：河北省药学会-医院药学科研项目,编号2020-Hbsyxhqn0020。

摘　　要：目的:调查某院门诊儿童常用药品说明书中有关儿童用药信息的标注情况,为药品说明书的完善和临床合理用药提供参考。方法:通过临床药学管理系统收集2020年4月至2021年3月某院门诊儿童患者(<16岁)处方中的药品,对药品说明书中的儿童用药信息标注情况进行调查分析。结果:全部药品(403个品种)说明书中标注儿童用药问题(包括禁用和不推荐使用)的药品说明书有72个(17.87%);儿童常用药品(143个)说明书中明确儿童用药剂量、儿童用药指导、儿童药物代谢动力学、儿童临床试验的标注率分别是35.66%、57.34%、9.79%、5.59%,其中最常用的药理学(功能)类别中,西药消化系统用药、免疫系统用药、皮肤科用药以及中成药内科用药的标注率较低,剂型类别中口服制剂的标注率较低,处方药非处方药类别中非处方药的标注率较低;儿童用药剂量确定方法中最常用的是固定剂量和按体质量确定剂量。结论:门诊儿童患者用药中涉及到儿童用药问题药品品种数量较多,且常用药品说明书中有关儿童用药信息的标注率不高,应在临床使用时加强管理,并不断完善药品说明书,从而保障儿童用药安全合理。Objective:To investigate the annotation of children’s medication information in instructions of commonly used drugs for children in outpatients of a hospital,so as to provide reference for the improvement of drug instructions and rational drug use in clinic.Methods:Through the clinical pharmacy management system,drugs in prescriptions of outpatient pediatric patients(less than 16 years old)in a hospital from Apr.2020 to Mar.2021 were collected,and the annotation of children’s medication information in the drug instructions was investigated and analyzed.Results:There were 72(17.87%)kinds of drugs had medication problems in children(including banned and not recommended drugs)in all drug instructions(403 categories).The annotation rates of drug dosage,drug guidance,pharmacokinetics and clinical trials in children in commonly used drug instructions(143 categories)were respectively 35.66%,57.34%,9.79%and 5.59%.Among the most commonly used pharmacological(functional)categories,the annotation rate of western drugs for digestive system,immune system,dermatology and internal medicine of Chinese patent medicine was relatively low,the annotation rate of oral preparations in dosage form category was relatively low,and the annotation rate of ethical drug and over the counter(OTC)drug category was relatively low.The most commonly used methods of dose determination for children were fixed dose and dose determination by body mass.Conclusion:There are a large number of problems related to children’s medication in outpatient pediatric patients,and the annotation rate of children’s medication information in commonly used drug instructions is lower.Therefore,it is necessary to strengthen the management in clinical use and constantly improve the drug instructions,so as to ensure the safety and rationality of children’s medication.

关 键 词：儿童 药品说明书 标注率 合理用药 

分 类 号：R969.3[医药卫生—药理学]