C臂X线辅助前列腺癌内置金标志物辨识的可行性研究  

Feasibility Study of C-Arm X-Ray-Assisted Identification of Implanted Gold Fiducial Marker in Prostate Cancer

作　　者：牛向欣 赵明娟 田龙[1] 胡逸民[3] NIU Xiangxin;ZHAO Mingjuan;TIAN Long;HU Yimin(Department of Medical Imaging,The First Affiliated Hospital of Hebei Northern University,Zhangjiakou Hebei 075000,China;Department of Medical Imaging,Hebei General Hospital,Shijiazhuang Hebei 050000,China;Department of Radiotherapy,Cancer Hospital of Chinese Academy of Medical Sciences,Beijing 100021,China)

机构地区：[1]河北北方学院附属第一医院医学影像科,河北张家口075000 [2]河北省人民医院医学影像科,河北石家庄050000 [3]中国医学科学院肿瘤医院放疗科,北京100021

出　　处：《中国医疗设备》2022年第6期85-88,共4页China Medical Devices

基　　金：张家口市重点研发计划(1921002B)。

摘　　要：目的研究C臂X线(C-arm X-ray,CX)kV级图像在基于MR图像的前列腺癌放疗计划设计中辅助辨识内置金标志物(Gold Fiducial Marker,GFM)的可行性。方法选择符合纳入、排除标准的32例前列腺癌患者,首先获取包含GFM的前后位CX图像和MR数字重建放射图像(MR-Digitally Reconstructured Radiograph,MR-DRR),对两图像上GFM中心进行匹配,计算头脚、左右方向和二维空间位移,进行CX辅助MR-DRR上GFM辨识。之后获取包含GFM的前后位CT数字重建放射图像(CT-Digitally Reconstructured Radiograph,CT-DRR)并辅助MR-DRR上的GFM辨识。对两种辨识方法在各方向上的差异进行统计学分析。结果CX辅助辨识方法中所有患者头脚、左右方向和二维平面位移平均值分别为(0.91±0.85)、(0.83±0.71)、(1.54±1.41)mm。CT辅助辨识方法的各平均值为(0.69±0.55)、(0.53±0.46)、(1.14±0.73)mm。两种辨识方法各向差异均具有统计学意义(P<0.05)。结论相对于CT,CX辅助辨识方法的准确度可以接受,具有一定临床应用价值。Objective To study the feasibility of C-arm X-ray(CX)kV image in prostate cancer radiotherapy plan design based on MR image for identification of implanted gold fiducial marker(GFM).Methods A total of 32 patients with prostate cancer who met the inclusion and exclusion criteria were selected.First,CX image and MR-digitally reconstructured radiograph(MR-DRR)with GFM in anterior-posterior direction were acquired.The center of GFM on two images was matched.Displacement in superior-inferior and left-right direction and two-dimension space was calculated.Auxiliary identification for GFM on MR-DRR with CX was performed.Then CT-digitally reconstructured radiograph(CT-DRR)with GFM in anterior-posterior direction was acquired and auxiliary identification for GFM on MR-DRR was performed.Difference in all directions between two auxiliary identification methods was statistically analyzed.Results Average value of displacement in superior-inferior and left-right direction and two-dimension space was(0.91±0.85),(0.83±0.71)and(1.54±1.41)mm,respectively in CX-assisted identification,and(0.69±0.55),(0.53±0.46)and(1.14±0.73)mm in CT-assisted identification.There was significant difference between two identification methods in all directions(P<0.05).Conclusion Compared with CT,the accuracy of CX-assisted identification method is acceptable and has certain clinical application value.

关 键 词：C臂X线 前列腺癌 辅助辨识方法 磁共振成像 

分 类 号：R737.25[医药卫生—肿瘤] R81[医药卫生—临床医学]