辽宁省城市地区居民恶性肿瘤10年生存率分析  

Ten-year Survival Rate Analysis of Cancer in Urban Areas of Liaoning Province

作　　者：穆慧娟[1] 礼彦侠[1] 于丽娅[1] 吕艺[2] 徐绍和[3] 安晓霞[4] 刘莉[1] 毛春莹 潘国伟 MU Hui-juan;LI Yan-xia;YU Li-ya;LYU Yi;XU Shao-he;AN Xiao-xia;LIU Li;MAO Chun-ying;PAN Guo-wei(Liaoning Provincial Center for Disease Control and Prevention,Shenyang 110005,China;Shenyang Municipal Center for Disease Control and Prevention,Shenyang 110031,China;Anshan Municipal Center for Disease Control and Prevention,Anshan 114009,China;Benxi Municipal Center for Disease Control and Prevention,Benxi 117000.China;China Medical University,Shenyang 110122,China)

机构地区：[1]辽宁省疾病预防控制中心,辽宁沈阳110005 [2]沈阳市疾病预防控制中心,辽宁沈阳110031 [3]鞍山市疾病预防控制中心,辽宁鞍山114009 [4]本溪市疾病预防控制中心,辽宁本溪117000 [5]中国医科大学,辽宁沈阳110122

出　　处：《中国肿瘤》2022年第4期269-275,共7页China Cancer

基　　金：辽宁省“兴辽英才计划”项目(XLYC1802131)。

摘　　要：[目的]分析辽宁省三城市21种恶性肿瘤的10年生存率情况。[方法]在辽宁省三城市2000—2002年肿瘤登记数据库中随机抽取恶性肿瘤病例,对其生存状况开展主动和被动随访。采用寿命表法计算观察生存率(OSR),使用EdererⅡ方法计算期望生存率(ESR),相对生存率(RSR)等于观察生存率除以期望生存率,使用辽宁三城市2000—2002年肿瘤登记数据库中分性别、年龄的癌症例数为权重进行加权;并使用国际癌症生存标准人群构成,采用直接标准化方法计算其标准化相对生存率(ASRS)。[结果]辽宁省三城市10年RSR为31.3%,男性和女性分别为23.3%和38.6%。10年相对生存率最高的癌种为甲状腺癌(74.6%)和子宫体癌(67.9%);胰腺癌(4.9%)和肝癌(5.0%)为生存率最低的癌种。两性癌种的10年ASRS中,仅有男性的膀胱癌(53.7%)、白血病(10.0%)和胃癌(19.4%)高于女性(依次为44.5%、6.1%和18.8%)。[结论]辽宁城市甲状腺癌和子宫体癌10年ASRS最高,肝癌和胰腺癌最低,辽宁省21种恶性肿瘤10年生存率趋势虽与经济发达国家和地区基本一致,但生存率水平仍有差距。[Purpose]To study the 10-year survival of cancer in urban areas of Liaoning Province.[Methods]Stratified random sampling was used to select patients from the cancer registries data of three cities in Liaoning Province from 2000 to 2002,and to carry out active and passive followup on their survival status.The observed survival rate was calculated by life table method,the expected survival rate was calculated by Ederer method,and the relative survival rate was obtained by dividing the observed survival rate by the expected survival rate.The cancer cases by gender and age in the cancer registration data of 3 cities in Liaoning Province from 2000 to 2002 were weighted.The standardized relative survival rate was calculated by direct standardization method using the population composition of international cancer survival standard.[Results]The 10-year RSR of the three cities in Liaoning Province was 31.3%,23.3%for males and 38.6%for females.The highest 10-year relative survival rates were thyroid cancer(74.6%)and corpus uteri cancer(67.9%).Pancreatic cancer(4.9%)and liver cancer(5.0%)had the lowest survival rates.Only bladder cancer(53.7%),leukaemia(10.0%)and stomach cancer(19.4%)were higher in men than those in women(44.5%,6.1%and 18.8%).[Conclusion]The 10-year ASRS of thyroid cancer and corpus uteri cancer are the highest in Liaoning Province,while those of liver cancer and pancreatic cancer are the lowest.Although the 10-year survival trend of 21 cancers in Liaoning Province is basically the same as that in developed countries and regions,there is still a gap in survival level.

关 键 词：恶性肿瘤 肿瘤登记 相对生存率 标准化相对生存率 辽宁 

分 类 号：R73-31[医药卫生—肿瘤]