急性胰腺炎356例抗菌药物使用情况调查  

Investigation of the use of antibiotics in 356 cases of acute pancreatitis

作　　者：祁旺 黄磊 卞海林 祁峰 QI Wang;HUANG Lei;BIAN Hailin;QI Feng(Pharmacy Department,The First People’s Hospital of Yancheng City,Yancheng,Jiangsu 224000,China)

机构地区：[1]盐城市第一人民医院药学部,江苏盐城224000

出　　处：《安徽医药》2022年第7期1470-1473,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的 调查分析急性胰腺炎(AP)病人的抗菌药物使用情况,提高AP抗感染治疗水平。方法 采用回顾性研究方法,利用HIS系统及电子病历系统收集盐城市第一人民医院消化科2019年1—12月收治的356例AP病人的基本信息,针对抗菌药物使用情况进行统计,对其使用合理性进行分析评价。结果 356例AP病人有348例(97.75%)使用了抗菌药物,使用例次排名前三的抗菌药物分别为莫西沙星169例(28.64%)、奥硝唑136例(23.05%)、头孢他啶112例(18.98%);初始治疗方案中抗菌药物联合使用有203例(57.02%),更换抗菌药物治疗方案的有30例(8.42%);共存在209例次用药不适宜情况,主要为无指征预防用抗菌药物158例(75.60%)。结论 抗菌药物在AP病人的应用中仍存在诸多不合理情况,应加强对临床医师的宣教及培训,促进合理使用。Objective To investigate and analyze the use of antibiotics in patients with acute pancreatitis(AP) to improve the effect of anti-infective therapy for AP.Methods tients admitted to the Department of Gastroenterology,The First People’s Hospital of Yancheng City,from January to December 2019by using the HIS system and electronic medical record system.Statistics on the use of antibiotics and analysis and evaluation of the rationality of their use.Results Among the 356 AP patients,348(97.75%) used antibiotics,and the top 3 antibiotics were moxifloxacin(169 cases,28.64%),ornidazole(136 cases,23.05%) and ceftazidime(112 cases,18.98%).In the initial therapeutic regimen,203 cases(57.02%) were used in combination with antibiotics,and 30 cases(8.42%) were replaced by an antibiotic therapeutic regimen.There were 209 cases of unsuitable drug use,mainly 158 cases(75.60%) of unindicated prophylactic antibiotics.Conclusions There are still many unreasonable situations in the application of antibacterial drugs in AP patients,and the education and training of clinicians should be strengthened to promote rational use.

关 键 词：胰腺炎 处方不当 抗菌药 莫西沙星 奥硝唑 头孢他啶 

分 类 号：R576[医药卫生—消化系统]