3D个性化打印模板联合CT引导^(125)I放射性粒子植入治疗颈部转移瘤的研究  

3D individualized printing template combined with CT-guided ^(125)I radioactive particle implantation versus pure CT-guided;I radioactive particle implantation for metastatic tumors of neck:a comparative study

作　　者：吴峰[1] 郭彦伟 徐红卫[1] 郭辉[1] 权红军[1] 夏燕娜 齐丽丹 WU Feng;GUO Yanwei;XU Hongwei;GUO Hui;QUAN Hongjun;XIA Yanna;QI Lidan(Department of Medical Imaging,Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan Province 450052,China)

机构地区：[1]郑州大学第五附属医院医学影像科,450052

出　　处：《介入放射学杂志》2022年第3期272-276,共5页Journal of Interventional Radiology

摘　　要：目的探讨3D个性化打印模板联合CT引导;I放射性粒子植入术在颈部转移瘤中的治疗效果。方法选取2016年5月至2017年5月颈部转移瘤患者20例,随机数字表法分为对照组(n=10)与研究组(n=10)。研究组采取3D个性化打印模板联合CT引导;I放射性粒子植入术,对照组常规实施CT引导;I放射性粒子植入术。比较两组计划粒子植入数目及实际粒子植入数目、粒子植入优良率、手术时间、临床疗效。术后随访6~9个月,统计两组疾病复发率。结果两组间计划粒子植入数目差异无统计学意义(P>0.05),研究组实际粒子植入数目多于对照组(P<0.05),且对照组实际粒子植入数目显著少于计划粒子植入数目(P<0.05);研究组粒子植入优良为9例,高于对照组的4例(P<0.05);研究组总有效为8例,高于对照组的4例,但组间比较差异无统计学意义(P>0.05)。研究组平均手术时间明显短于对照组;研究组术后6个月及9个月疾病复发分别为1例,2例,低于对照组的3例和5例,但组间差异无统计学意义(P>0.05)。结论采取3D个性化打印模板联合CT引导;I粒子植入治疗颈部转移瘤,实际粒子植入数目与计划数目较接近,粒子植入优良率较高,可有效提高疾病治疗效果、降低疾病复发率。Objective To investigate the curative effect of 3D individualized printing template combined with CT-guided;I radioactive particle implantation in treating metastatic tumors of neck.Methods A total of 20 patients with metastatic tumor of neck,who were admitted to authors’hospital between May 2016and May 2017,were collected.By using random number table method,the patients were divided into control group(n=10)and study group(n=10).3D individualized printing template combined with CT-guided;I radioactive particle implantation was performed for the patients of the study group,while conventional CT-guided;I radioactive particle implantation was adopted for the patients of the control group.The numbers of both planned implanted particles and actual implanted particles,the excellent implantation rate of particles,the time spent for operation and the clinical efficacy in the two groups were calculated.After operation,the patients were followed up for 6-9 months,the disease recurrence rate in the two groups were also calculated.Results There was no significant difference in the number of planned implantation particles between the two groups(P>0.05).In the study group the number of actual implanted particles was prominently larger than that in the control group(P<0.05),and in the control group the number of actual implanted particles was remarkably less than the number of planned implantation particles(P<0.05).The excellent implantation rate of particles in the study group was 90.0%,which was strikingly higher than 40.0%in the control group(P<0.05).The total effective rate in the study group was 80.0%,which was higher than 40.0%in the control group,although the difference between the two groups was not statistically significant(P>0.05).The mean time spent for operation in the study group was obviously shorter than that in the control group.The postoperative 6-month and 9-month recurrence rates in the study group were 10%and 20%respectively,which were lower than 30%and 50%respectively in the control group,although the dif

关 键 词：3D个性化打印模板 CT引导 I放射性粒子植入 颈部转移瘤 

分 类 号：R739.9[医药卫生—肿瘤]