机构地区:[1]重庆市疾病预防控制中心慢性病预防控制所,重庆400042 [2]重庆市永川区儿童医院,重庆402160
出 处:《中国慢性病预防与控制》2022年第4期273-277,共5页Chinese Journal of Prevention and Control of Chronic Diseases
基 金:重庆市科卫联合项目(2021MSXM198)。
摘 要:目的 了解重庆市肺癌发病率及长期变化趋势,为完善肺癌防治措施提供建议。方法 利用2006—2020年重庆市肿瘤登记点肺癌新发个案数据,采用SPSS 25.0分析肺癌发病率、标化发病率、年龄别发病率,不同性别、地区间肺癌发病率的比较采用χ;检验,采用SPSS 25.0进行率的趋势变化分析,计算年度变化百分比(APC)和平均年度变化百分比(AAPC)。结果 重庆市肺癌发病率与标化发病率由2006年的37.52/10万、33.31/10万上升至2020年的78.59/10万、42.21/10万,AAPC分别为4.92%与1.90%,均有统计学意义(P<0.01)。2006—2020年男性肺癌发病率与标化发病率分别以年均4.71%与3.36%的比例上升,变化趋势均有统计学意义(P<0.01)。2006—2020年女性肺癌发病率以年均5.65%的比例上升,变化趋势有统计学意义(P<0.01),但标化发病率变化趋势无统计学意义(P>0.05)。历年男性肺癌发病率均高于女性,差异均有统计学意义(P<0.01)。2006—2020年城市肺癌发病率与标化发病率分别以年均3.56%与1.92%的比例上升,变化趋势均有统计学意义(P<0.01)。农村地区肺癌发病率与标化发病率分别以年均6.50%与2.43%的比例上升,变化趋势均有统计学意义(P<0.01)。除2006年、2015年、2017年与2018年外,其余年份城市肺癌发病率均高于农村,差异均有统计学意义(P<0.05,P<0.01)。2020年重庆市<40岁人群肺癌发病率低,>40岁人群发病率随年龄增长而上升。50~59、60~69和70~79岁人群肺癌发病率2006—2020年分别以年均1.92%、3.05%和1.92%的速度上升,变化趋势均有统计学意义(P<0.05)。结论 重庆市肺癌发病率高,并且呈快速上升的趋势,应针对不同人群采取更有针对性的防控措施。Objective To understand the long-term trend of lung cancer incidence from 2006 to 2020 in Chongqing,and provide the suggestion for improving measures of lung cancer prevention and treatment. Methods Cases of lung cancer from cancer registration sites from 2006 to 2020 in Chongqing were used. The incidence,age standardized incidence,age-specific incidence of lung cancer were analyzed;the χ~2test was used to compare the lung cancer incidence between different gender and areas;the software SPSS 25.0 was used to analyze the trend change of lung cancer incidence,and calculate the annual percent of change(APC) and average annual percent of change(AAPC). Results The incidence and standardized incidence of lung cancer in Chongqing increased from 37.52/105and 33.31/10~5in 2006 to 78.59/105and 42.21/10~5in 2020,AAPCs were 4.92% and 1.90%,P <0.01. From 2006 to 2020,the incidence and standardized incidence of male lung cancer increased,AAPCs were 4.71% and3.36%(P<0.01);the incidence of female lung cancer increased,AAPC=5.65%(P<0.01),but there was no significant difference of standardized incidence change trend(P>0.05).The incidence of lung cancer in males was significantly higher than that in females every year(P<0.01). From 2006 to 2020,the incidence and standardized incidence of lung cancer in urban areas increased,AAPCs were 3.56% and 1.92%(P<0.01);the incidence and standardized incidence of lung cancer in rural areas increased,AAPCs were6.50% and 2.43%(P<0.01). Except for 2006,2015,2017 and 2018,the incidences of lung cancer in urban areas in other times were significantly higher than those in rural areas(P<0.05 or P<0.01). The incidence of lung cancer before 40 years old was lower,but increased with age after 40 years old. From 2006 to 2020,the incidences of lung cancer in 50-59,60-69 and 70-79 years old groups increased,AAPCs were 1.92%,3.05% and 1.92%,respectively(P<0.05). Conclusion The incidence of lung cancer is high and increase rapidly in Chongqing. It should take the pertinent measures for lung cancer control a
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