贲门失弛缓症的发病机制研究进展  

Advances in the pathogenesis of achalasia of cardia

作　　者：谢文星 赵静 杨丽娜(综述) 蒋海涛 王红(审校) XIE Wen-xing;ZHAO Jing;YANG Li-na;JIANG Hai-tao;WANG Hong(Department of Gastroenterology,Affiliated Hospital of Zunyi Medical University,Zunyi 563000,Guizhou,CHINA)

机构地区：[1]遵义医科大学附属医院消化内科,贵州遵义563000

出　　处：《海南医学》2022年第12期1606-1609,共4页Hainan Medical Journal

基　　金：贵州省遵义市科技计划项目(编号:科合HZ字【2019】103号)。

摘　　要：贲门失弛缓症(AC)是一种特发性食管运动功能障碍性疾病,以食管蠕动异常、食管下括约肌(LES)松弛障碍为主要特点。发病机制目前尚无明确,但一般认为遗传、病毒及免疫相关因素等病因可能共同作用导致LES松弛障碍及食管蠕动异常,通过一系列反应引起AC的发生。Achalasia(AC)is an idiopathic esophageal motor dysfunction disease characterized by abnormal esophageal peristalsis and relaxation of the lower esophageal sphincter(LES).The pathogenesis has not yet been clearly reported,but to a large extent,it is believed that genetic,viral,and immune-related factors may work together to cause LES slack and abnormal esophageal motility,and cause AC through a series of reactions.

关 键 词：贲门失弛缓症 食管下段括约肌 发病机制 病因 

分 类 号：R571[医药卫生—消化系统]