呼吸动度对食管癌靶区影响及呼吸运动管理策略  

Effect of Respiratory Movement on Esophagus Cancer Target Volume and Respiratory Motility Management Stratege

作　　者：刘慧[1,2] 付雅 皈燕 阳华东[1] 柳弥[1] LIU Hui;FU Ya;GUI Yan;YANG Hua-dong;LIU Mi(Department of Oncology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of Clinical Medicine,North Sichuan Medical College,Nanchong 637000,Sichuan,China)

机构地区：[1]川北医学院附属医院肿瘤科,四川南充637000 [2]川北医学院临床医学系,四川南充637000

出　　处：《医学信息》2022年第12期93-96,共4页Journal of Medical Information

基　　金：川北医学院科研发展青年项目(编号:CBY20-QA-Y05)。

摘　　要：食管癌放疗期间由于自主和不自主运动,各器官位置常与定位时有区别,使计划靶区和实际靶区剂量吻合程度误差增大。食管因其自身结构及解剖特点,靶区位置变化受多种因素影响,以呼吸运动影响最为显著。呼吸运动可导致靶区漏照、正常组织受照射量过大等问题,导致肿瘤局部控制率降低,增加放疗副反应,因此呼吸运动管理尤为重要。呼吸运动管理分为被动管理和主动管理技术,前者为靶区的外扩,后者包括压腹、呼吸门控以及肿瘤跟踪技术,可从不同方面实现肿瘤的“精准放疗”。本文主要就食管癌放疗中呼吸动度的影响和呼吸运动管理作一综述,以期为该病的临床治疗提供帮助。During radiotherapy for esophageal cancer,due to voluntary and involuntary movement,the position of each organ is often different from that of positioning,which increases the error of dose coincidence between the planned target area and the actual target area.Because of its own structure and anatomical characteristics,esophageal target location changes are affected by many factors,especially respiratory movement.It causes problems such as missed radiation in the target area and excessive radiation exposure to normal tissues,which can reduce local control rate,and increase the side effects of radiotherapy.Therefore,respiratory movement management is particularly important.Respiratory motion management is divided into passive management and active management technology.The former is the expansion of the target area,and the latter includes abdominal compression,respiratory gating and tumor tracking technology,which can realize "precision radiotherapy" of tumors from different aspects.This article mainly reviews the influence of respiratory motility and respiratory movement management in radiotherapy for esophageal cancer,in order to provide help for clinical treatment of the disease.

关 键 词：食管癌 放射治疗 呼吸运动管理 

分 类 号：R735.1[医药卫生—肿瘤]