颅内动脉瘤患者介入栓塞术后脑供血不足发生的影响因素分析  

Analysis on influencing factors of insufficiency of cerebral blood supply in patients with intracranial aneurysms after interventional embolization

作　　者：魏海亮[1] 程夏飞 裴献光[1] 李翠君 李建华[1] 王志强[1] WEI Hailiang;CHENG Xiafei;PEI Xianguang;LI Cuijun;LI Jianhua;WANG Zhiqiang(Handan First Hospital,Handan,Hebei 056002,China)

机构地区：[1]邯郸市第一医院,河北省邯郸市056002

出　　处：《中南医学科学杂志》2022年第3期402-404,共3页Medical Science Journal of Central South China

基　　金：邯郸市科学技术研究与发展计划项目(1423108127)。

摘　　要：目的分析颅内动脉瘤(IA)患者介入栓塞术后脑供血不足发生的影响因素。方法回顾性分析接受介入栓塞术治疗的90例IA患者病例资料、相关检查资料;统计患者术后3周脑供血不足发生情况,设计基线资料填写表,阅读并记录患者相关基线资料,将可能的影响因素纳入,经Logistic回归分析找出可能导致IA患者介入栓塞术后脑供血不足发生的影响因素。结果90例IA患者术后有13例发生脑供血不足,发生率为14.44%;IA患者脑供血不足发生者动脉瘤最大径、吸烟史、合并高血压、Hunt-Hess分级、甘油三酯(TG)水平、总胆固醇(TC)水平与未发生脑供血不足者比较,差异有显著性(P<0.05);经Logistic回归分析,动脉瘤最大径>10 mm、合并高血压、TG和TC水平升高可能是IA患者介入栓塞术后脑供血不足发生的危险因素(P<0.05)。结论IA患者介入栓塞术后脑供血不足可能与动脉瘤最大径>10 mm、合并高血压、TG和TC水平升高有关。Aim To analyze the influencing factors of insufficiency of cerebral blood supply in patients with intracranial aneurysm(IA)after interventional embolization.Methods A retrospective analysis was conducted,the data of 90 patients with IA who received interventional embolization for treatment were collected,the case data and related examination data of patients were complete;the occurrence of insufficiency of cerebral blood supply in patients 3 weeks after operation was counted,the baseline data filling form was designed,the baseline data of patients was read and recorded,the possible influencing factors were included,Logistic regression analysis was used to find out the influencing factors of insufficiency of cerebral blood supply in IA patients after interventional embolization.Results Among 90 patients with IA after operation,13 patients had insufficiency of cerebral blood supply,the incidence was 14.44%;the maximum diameter of aneurysm,smoking history,hypertension,Hunt-Hess grade,triglyceride(TG)level and total cholesterol(TC)level in IA patients with cerebral insufficiency were significantly different from those without IA,with a statistical significant difference(P<0.05);through Logistic regression analysis,the results showed that the maximum diameter of aneurysm>10 mm,hypertension and the increase of TG and TC levels might be the influencing factors of cerebral insufficiency after interventional embolization in IA patients(P<0.05).Conclusion Insufficiency of cerebral blood supply in IA patients after interventional embolization may be affected by aneurysm diameter>10 mm,combined with hypertension,increased TG and TC levels.

关 键 词：颅内动脉瘤 介入栓塞术 脑供血不足 高血压 吸烟 

分 类 号：R743[医药卫生—神经病学与精神病学]