Lymphocyte count and A-DROP score in COVID-19 patients: A retrospective observational study  

作　　者：Chandrakant Waikar Vinayak Gour Lal Pranay Sevras Hingwe 

机构地区：[1]Departments of Anaesthesiology,ABV Medical College,Vidisha,India [2]Departments of Pathology,ABV Medical College,Vidisha,India

出　　处：《Journal of Acute Disease》2022年第3期115-119,共5页急性病杂志（英文版）

摘　　要：Objectives:To determine the correlation between lymphocyte count and A-DROP score in COVID-19 patients and their role in predicting poor outcomes.Methods:This retrospective observational single-center study was conducted in a tertiary care hospital in Vidisha district,India.COVID-19 patients were included in this study,who were admitted to ICU and the COVID Care Centre from August 2020 to October 2020.Demographic profile,clinical characteristics,medical history,A-DROP score,complete blood counts including lymphocyte counts(on admission),the severity of the disease course,and duration of hospitalization were collected.The correlation between lymphopenia and A-DROP score was determined,and their role in predicting poor outcomes was investigated.Results:This study included 220 patients,among which 134 were male,and 86 were female[mean age(48.98±16.98)years,95%CI:46.72-51.23].Lymphocyte count in COVID-19 patients negatively correlated with the A-DROP score(r=-0.67,P<0.001).The area under the ROC curve was 0.892(95%CI:0.80-0.98,P<0.001)for the lymphocyte count,and the area under the ROC curve was 0.93(95%CI:0.84-1.00,P<0.001)for lymphocyte count-A-DROP.Conclusion:Lymphocyte count along with the A-DROP score on admission could be used to predict the severity of COVID-19 pneumonia and unfavorable outcome.

关 键 词：COVID-19 PANDEMIC LYMPHOPENIA PNEUMONIA 

分 类 号：R73[医药卫生—肿瘤]