后肾腺瘤临床病理特征及文献复习(附12例)  

Clinicopathological features and literature review of metanephric adenoma(12 cases)

作　　者：郑洪彦[1] 陈英准[1] ZHENG Hongyan;CHEN Yingzhun(Pathology Depertment,the Second Affiliated Hospital of Harbin Medical University,Heilongjiang Harbin 150086,China)

机构地区：[1]哈尔滨医科大学附属第二医院病理科,黑龙江哈尔滨150086

出　　处：《现代肿瘤医学》2022年第14期2612-2615,共4页Journal of Modern Oncology

摘　　要：目的:探讨后肾腺瘤(metanephric adenoma,MA)的临床病理特征、诊治、预后及其鉴别诊断。方法:回顾性分析12例MA的临床病理特征、免疫组化结果及治疗预后。结果:12例后肾腺瘤均为境界清楚的肿块;肿瘤细胞形态温和,小而密集,排列成腺泡状、乳头状、分枝小管状,间质不明显;细胞丰富,核圆形、卵圆形,无核仁,染色质细腻,胞浆稀少,淡染,少见核分裂象;部分可见砂粒体样钙化。免疫组织化学染色WT-1、CD57、PAX8、Vimentin、PAX2阳性,CK7、CD10、CD117阴性。结论:后肾腺瘤为一种罕见的肾脏上皮源性良性肿瘤,临床特征不明显,具有独特的组织病理学特征,免疫组化染色对其诊断具有重大意义,治疗以手术为主,完整切除预后良好。Objective:To investigate the clinicopathological features,diagnosis and treatment,prognosis and differential diagnosis of metanephric adenoma(MA).Methods:Retrospectively analysis the clinicopathological features,immunohistochemical features and treatment prognosis of 12 cases of MA.Results:All tumors were masses with a clear boundary.They also had distinct feature in histology as small cells with high ratio of nucleus to cytoplasm,no nuclear atypia or mitotic figures.The tumor exhibited well-organized tubules,papillary and branching tubules without stroma.Sand-like calcification was occasionally seen.The expression of WT-1、CD57、PAX8、Vimentin and PAX2 were positive while CK7、CD10、CD117 were negative.Conclusion:MA is a rare kidney primary epithelial origin benign tumor.The clinical features are not obvious and have unique histopathological characteristics.Immunohistochemical staining is of great significance for the diagnosis of the disease.The treatment was mainly surgical,with a good prognosis after complete resection.

关 键 词：后肾腺瘤 临床病理特征 免疫组织化学 

分 类 号：R737.11[医药卫生—肿瘤]