脑胶质瘤诊疗进展  

Current Progress in Treatment of Glioma

作　　者：张宇 何堃宇 冯世宇[2] ZHANG Yu;HE Kunyu;FENG Shiyu(Department of Neurosurgery,School of Clinical Medicine,Hebei University,Baoding 071000,China;Department of Neurosurgery,The First Medical Center of Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]河北大学临床医学院神经外科,保定071000 [2]解放军总医院第一医学中心神经外科,北京100853

出　　处：《肿瘤防治研究》2022年第6期528-534,共7页Cancer Research on Prevention and Treatment

摘　　要：尽管目前脑胶质瘤的诊断随着WHO诊断指南的更新在不断改变,但是目前的治疗方法依然以手术治疗为主、辅以放疗和化疗。高级别脑胶质瘤的治疗效果仍不如人意,如何改善患者预后是目前医学探索脑胶质瘤领域的重点问题。目前脑胶质瘤的诊疗研究涌现出许多新思路、新方法,其中以电场治疗为代表的一部分临床试验取得了较好的效果,此外,免疫治疗领域和靶向治疗领域也有了一定的进展。本文旨在分享、探讨这些新方法,总结脑胶质瘤诊疗进展。Although the diagnosis of glioma is constantly changing with the update of WHO diagnostic guidelines,the current treatment methods are still mainly surgical treatment,supplemented by radiotherapy and chemotherapy.It is a pity that the treatment effect of high-grade glioma is still unsatisfactory.How to improve the prognosis of patients is the key problem in the field of medical exploration of glioma.It is gratifying that many new ideas and methods have emerged in the diagnosis and treatment of glioma,in which some trials represented by tumor treating fields have achieved good results in clinical research,moreover,the fields of immunotherapy and targeted therapy have developed too.This paper aims to share and explore these new methods and summarize the progress of diagnosis and treatment of glioma.

关 键 词：胶质瘤 分子病理 靶向治疗 免疫治疗 电场治疗 

分 类 号：R739.41[医药卫生—肿瘤]