奥美拉唑碳酸氢钠胶囊治疗胸下段食管癌术后反流性食管炎的疗效分析  

Effect of Omeprazole Sodium Bicarbonate Capsule on Reflux Esophagitis after Operation of Lower Thoracic Esophageal Cancer

作　　者：杨晓利[1] 夏金[1] YANG Xiao-li;XIA Jin(Department of Internal Medicine,Anyang Tumor Hospital,Anyang,China,455000)

机构地区：[1]安阳市肿瘤医院内科,河南安阳455000

出　　处：《食管疾病》2022年第2期137-139,共3页Journal of Esophageal Diseases

摘　　要：目的观察奥美拉唑碳酸氢钠胶囊治疗胸下段食管癌术后反流性食管炎的疗效。方法选取我院2018年3月至2020年3月因胸下段食管癌行食管胃吻合术后有反流性食管炎的患者共180例,随机分为观察组和对照组各90例。对照组应用奥美拉唑肠溶胶囊联合莫沙必利,观察组应用奥美拉唑碳酸氢钠胶囊和莫沙必利,比较两组症状缓解情况、内镜下食管黏膜炎症改善情况以及不良反应。结果奥美拉唑碳酸氢钠组治疗后疗效明显高于对照组(P<0.05)。结论对于胸下段食管癌术后合并反流性食管炎的患者,使用奥美拉唑碳酸氢钠胶囊联合莫沙必利疗效更好。Objective To observe the efficacy of omeprazole sodium bicarbonate capsule in the treatment of reflux esophagitis after operation of lower thoracic esophageal cancer.Methods A total of 180 patients with reflux esophagitis after esophagogastrostomy for lower thoracic esophageal cancer in our hospital from March 2018 to March 2020 were randomly divided into observation group and control group.The observation group received omeprazole sodium bicarbonate capsule and mosapride tablet.The control group received omeprazole and mosapride.The symptom relief,improvement of esophageal mucosal inflammation under endoscopy and adverse reactions were compared between the two groups.Results The clinical effective rate in the observation group was significantly higher than that in the control group(P<0.05).Conclusion Integrating Omeprazole Sodium Bicarbonate capsule and Mosapride has higher medicinal value in clinical treatment options for reflux esophagitis after lower esophagectomy,which is worthy of clinical application.

关 键 词：胸下段食管癌 反流性食管炎 奥美拉唑碳酸氢钠胶囊 莫沙必利 

分 类 号：R735.1[医药卫生—肿瘤]